Optimized pathological and visual content-based neuroimaging retrieval

Sidong Liu, Weidong Cai, Lingfeng Wen, Stefan Eberl, Michael Fulham, Dagan Feng

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review


Neuroimaging provides important insights for understanding neurobiology and is essential for accurate neurological and neurosurgical diagnosis and patient care. The volume and complexity of the neuroimaging datasets have greatly increased due to advances in scanning instrumentation. These large datasets now pose challenges for images retrieval / management and more effective approaches are needed. Content-based image retrieval (CBIR) takes advantage of the rich visual/physiological information in the images and can provide the opportunity for more efficient and reliable image retrieval. Although a number of investigators have used CBIR systems in neuroimaging, few of these approaches have explored all the potential features in these images. We suggest that such image retrieval could be optimized by using pathological and domain-specific visual features rather than texture features alone. We used the cerebral metabolic rate of glucose (CMRGlc) as the physiological parameter from static brain [ 18F] 2-fluorodeoxy-glucose (FDG) positron emission tomography (PET) images and a customized disorder-oriented mask (DOM) specific for a particular neurodegenerative disorder, with the regions of interest (ROIs) specific for each disease sub-type. We designed 8 Gabor filter banks with different parameter settings and identified the optimum Gabor function parameter setting for the visual feature extraction. Our experimental data indicate that optimization of the Gabor filter parameters, targeted to disease specific regions enhances retrieval precision.
Original languageEnglish
Title of host publicationProceedings of International Society for Optical Engineering (SPIE) Medical Imaging Conference
Number of pages7
ISBN (Print)0277-786X
Publication statusPublished - Feb 2011
Externally publishedYes
EventMedical Imaging 2011: Image Processing - Lake Buena Vista, FL, United States
Duration: 14 Feb 201116 Feb 2011


OtherMedical Imaging 2011: Image Processing
Country/TerritoryUnited States
CityLake Buena Vista, FL


  • neurological image
  • image retrieval
  • positron emission tomography
  • dementia


Dive into the research topics of 'Optimized pathological and visual content-based neuroimaging retrieval'. Together they form a unique fingerprint.

Cite this