Optoacoustic measurement of nanoparticle degradation in physiological media

I. V. Zelepukin*, A. V. Zvyagin, S. M. Deyev

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference abstractpeer-review

Abstract

Here we demonstrate application of optoacoustic technology for real-time measurement of inorganic nanoparticle degradation. We analysed kinetics of silicon nanoparticle dissolution in various physiological buffers. Silicon shows acceleration of degradation rate with the increase of pH and salt concentration. Screening dissolution rate of light-absorbing nanoparticles with optoacoustics can improve rational design of drug carriers for biomedical applications.

Original languageEnglish
Title of host publicationICLO 2022
Subtitle of host publicationProceedings of the 2022 International Conference Laser Optics
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Number of pages1
ISBN (Electronic)9781665466646
DOIs
Publication statusPublished - 2022
Event2022 International Conference Laser Optics, ICLO 2022 - St. Petersburg, Russian Federation
Duration: 20 Jun 202224 Jun 2022

Publication series

NameInternational Conference Laser Optics
ISSN (Print)2642-5580

Conference

Conference2022 International Conference Laser Optics, ICLO 2022
Country/TerritoryRussian Federation
CitySt. Petersburg
Period20/06/2224/06/22

Keywords

  • biodegradation
  • degradation
  • nanoparticles
  • optoacoustics
  • silicon

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