Organoids for advanced therapeutics and disease models

Suran Kim, Ann-Na Cho, Sungjin Min, Sooyeon Kim, Seung-Woo Cho*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Citations (Scopus)


Organoid culture is a fast‐emerging technology in the biological and biomedical research fields, garnering interest due to its unique features of self‐organization from diverse types of stem cells and close resemblance to organs in the human body. This innovative in vitro model system presents the possibility of significant advances in the understanding of human development and disease mechanisms as well as in the discovery of novel diagnostics and therapeutics. Here, the authors review several types of tissue‐specific organoids and discuss the most recent studies on the biomedical application of organoids. Finally, the challenges and prospects of organoids as an in vitro model system are laid out.
Original languageEnglish
Article number1800087
Pages (from-to)1-16
Number of pages16
JournalAdvanced Therapeutics
Issue number1
Publication statusPublished - Jan 2019
Externally publishedYes


  • disease modeling
  • drug screening
  • organoids
  • regenerative medicine
  • stem cells


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