Osteolysis after silicone arthroplasty

S. L. Harboldt, G. J. Gumley, K. Balogh*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


A young woman with a silicone lunate prosthesis for avascular necrosis developed painful lytic lesions in the distal ulna and the triquetrum. At reoperation, abundant reactive synovitis was found extending into those bone lesions. Histologic examination of the curetting samples revealed granulation tissue with histiocytes and many multinucleated giant cells containing refractile particles consistent with silicone. The authors report a giant cell lesion of the bone that radiographically and microscopically mimicked a neoplasm.

Original languageEnglish
Pages (from-to)594-597
Number of pages4
JournalAmerican Journal of Clinical Pathology
Issue number6
Publication statusPublished - 1992
Externally publishedYes


  • Giant cell lesion of bone
  • Silicone arthroplasty
  • Silicone osteolysis
  • Silicone synovitis


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