Paralogous genes encoding transport proteins in microbial genomes

Milton H. Saier; Ian T. Paulsen

doi:10.1016/S0923-2508(99)00123-0

Paralogous genes encoding transport proteins in microbial genomes

Milton H. Saier, Ian T. Paulsen

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

The largest superfamilies of prokaryotic genes encode transport proteins, but many transporters are encoded by orphan genes or those that comprise very small families. We have analyzed eighteen completely sequenced prokaryotic genomes for paralogous transport systems and have thereby identified 76 permease families. In this short review, we present and discuss the paralogues in some of these families and interpret the most prominent results, particularly those relevant to the largest permease superfamilies.

Original language	English
Pages (from-to)	689-699
Number of pages	11
Journal	Research in Microbiology
Volume	150
Issue number	9-10
DOIs	https://doi.org/10.1016/S0923-2508(99)00123-0
Publication status	Published - Nov 1999
Externally published	Yes

Keywords

Evolution
Paralogue
Permease family
Superfamily
Transport protein

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10.1016/S0923-2508(99)00123-0

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title = "Paralogous genes encoding transport proteins in microbial genomes",

abstract = "The largest superfamilies of prokaryotic genes encode transport proteins, but many transporters are encoded by orphan genes or those that comprise very small families. We have analyzed eighteen completely sequenced prokaryotic genomes for paralogous transport systems and have thereby identified 76 permease families. In this short review, we present and discuss the paralogues in some of these families and interpret the most prominent results, particularly those relevant to the largest permease superfamilies.",

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author = "Saier, {Milton H.} and Paulsen, {Ian T.}",

year = "1999",

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AU - Saier, Milton H.

AU - Paulsen, Ian T.

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AB - The largest superfamilies of prokaryotic genes encode transport proteins, but many transporters are encoded by orphan genes or those that comprise very small families. We have analyzed eighteen completely sequenced prokaryotic genomes for paralogous transport systems and have thereby identified 76 permease families. In this short review, we present and discuss the paralogues in some of these families and interpret the most prominent results, particularly those relevant to the largest permease superfamilies.

KW - Evolution

KW - Paralogue

KW - Permease family

KW - Superfamily

KW - Transport protein

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U2 - 10.1016/S0923-2508(99)00123-0

DO - 10.1016/S0923-2508(99)00123-0

M3 - Review article

C2 - 10673007

AN - SCOPUS:0343384158

VL - 150

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EP - 699

JO - Research in Microbiology

JF - Research in Microbiology

SN - 0923-2508

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ER -

Paralogous genes encoding transport proteins in microbial genomes

Abstract

Keywords

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