Parental smoking and childhood obesity

higher effect estimates for maternal smoking in pregnancy compared with paternal smoking-a meta-analysis

Christina Riedel*, Katharina Schönberger, Segumi Yang, Gibby Koshy, Yang-Chin Chen, Bamini Gopinath, Stephanie Ziebarth, Rüdiger von Kries

*Corresponding author for this work

Research output: Contribution to journalArticle

53 Citations (Scopus)


Background: Some studies reported similar effect estimates for the impact of maternal smoking in pregnancy and paternal smoking on childhood obesity, whereas others suggested higher effects for maternal smoking. We performed a meta-analysis to compare the effect of in utero exposure to maternal smoking and that of paternal or household smoking exposure in utero or after birth with mutual adjustment. Methods: Meta-analysis of observational studies identified in MEDLINE, EMBASE and Web of Knowledge published in 1900-2013. Study inclusion criterion was assessment of the association of maternal smoking during pregnancy and paternal or household smoking (anyone living in the household who smokes) at any time with childhood overweight and obesity. The analyses were based on all studies with mutually adjusted effect estimates for maternal and paternal/household smoking applying a random-effects model. Results: Data for 109 838 mother/child pairs were reported in 12 studies. The pooled odds ratios (ORs) for overweight 1.33 [95% confidence interval (CI) 1.23;1.44] (n=6, I 2=0.00%) and obesity 1.60 (95% CI 1.37;1.88) (n=4, I 2=32.47%) for maternal smoking during pregnancy were higher than for paternal smoking: 1.07 (95% CI 1.00;1.16) (n=6, I 2=41.34%) and 1.23 (95% CI 1.10;1.38) (n=4, I 2=14.61%), respectively. Similar estimates with widely overlapping confidence limits were found for maternal smoking during pregnancy and childhood overweight and obesity: 1.35 (95% CI 1.20;1.51) (n=3,I 2=0.00%) and 1.28 (95% CI 1.07;1.54) (n=3, I 2=0.00%) compared with household smoking 1.22 (95% CI 1.06;1.39) (n=3, I 2=72.14%) and 1.31 (95% CI 1.15;1.50)] (n=3, I 2=0.00%). Conclusions: Higher effect estimates for maternal smoking in pregnancy compared with paternal smoking in mutually adjusted models may suggest a direct intrauterine effect.

Original languageEnglish
Pages (from-to)1593-1606
Number of pages14
JournalInternational Journal of Epidemiology
Issue number5
Publication statusPublished - Oct 2014
Externally publishedYes


  • maternal smoking
  • paternal smoking
  • household smoking
  • obesity
  • overweight
  • meta-analysis

Fingerprint Dive into the research topics of 'Parental smoking and childhood obesity: higher effect estimates for maternal smoking in pregnancy compared with paternal smoking-a meta-analysis'. Together they form a unique fingerprint.

Cite this