Abstract
An ultrastructural study is described which relates cellular activity in the intermediate lobe of the pituitary gland with circulating levels of corticosterone. Exposure of male CSF rats to a signalled, unpredictable 60-day stress regimen induced intense secretory activity in all cells of the pars intermedia for the first 5 days of stressing, and thereafter secretory activity reverted back to the control condition. Blood corticosterone levels showed an initial extreme increase lasting for the first 5 days of exposure to the stress before gradually falling to re-establish a new stable level of secretion by 40 days. The possible involvement of the intermediate lobe in emotional or psychological stress when corticosterone levels are high is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 239-243 |
| Number of pages | 5 |
| Journal | Journal of Endocrinology |
| Volume | 99 |
| Issue number | 2 |
| Publication status | Published - 1983 |