Past oral contraceptive use and self-reported high blood pressure in postmenopausal women

Christine L. Chiu, Joanne M. Lind*

*Corresponding author for this work

Research output: Contribution to journalArticle

7 Citations (Scopus)
2 Downloads (Pure)

Abstract

Background: Studies have reported current hormonal contraceptive use is associated with adverse cardiovascular outcomes, including high blood pressure. The aim of this study was to determine the association between past hormonal contraception use and high blood pressure in Australian postmenopausal women. Methods: Women were recruited from the 45 and Up Study, an observational cross-sectional study, conducted from February 2006 to December 2009, NSW Australia. All of the variables used in this study were derived from self-reported data. These women reported being postmenopausal, having an intact uterus, and had given birth to one or more children. Odds ratios and 99% confidence intervals for the association between past hormonal contraceptive use and current treatment for high blood pressure, stratified by current age (<58 yrs, 58-66 yrs, and ≥67 yrs) were estimated using logistic regression, adjusted for income, country of origin, BMI, smoking, alcohol, exercise, family history of high blood pressure, menopausal hormone therapy use, number of children, whether they breastfed, and age of menopause. Results: A total of 34,289 women were included in the study. No association between past hormonal contraception use and odds of having high blood pressure were seen in any of the age groups (<58 yrs: odds ratio (OR) 1.1, 99% confidence interval (CI) 0.8 to 1.5, p∈=∈0.36; 58-66 yrs: OR 0.9, 99% CI 0.7 to 1.1, p∈=∈0.11; and ≥67 yrs: OR 0.9, 99% CI 0.8 to 1.0. p∈=∈0.06). In women with a history of hormonal contraception use, no association between duration of hormonal contraception use and high blood pressure was observed. Conclusions: Past hormonal contraception use and duration of use is not associated with high blood pressure in postmenopausal women.

Original languageEnglish
Article number54
Pages (from-to)1-6
Number of pages6
JournalBMC Public Health
Volume15
DOIs
Publication statusPublished - 2015
Externally publishedYes

Bibliographical note

Copyright the Author(s) 2015. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • High blood pressure
  • Hormonal contraception
  • Postmenopausal women

Fingerprint Dive into the research topics of 'Past oral contraceptive use and self-reported high blood pressure in postmenopausal women'. Together they form a unique fingerprint.

Cite this