Pathological analysis of lymph nodes in anterior prostatic fat excised at robot-assisted radical prostatectomy

Jonathan J. Aning; R. Thurairaja; D. A. Gillatt; A. J. Koupparis; E. W. Rowe; J. Oxley

doi:10.1136/jclinpath-2014-202303

Pathological analysis of lymph nodes in anterior prostatic fat excised at robot-assisted radical prostatectomy

Jonathan J. Aning^*, R. Thurairaja, D. A. Gillatt, A. J. Koupparis, E. W. Rowe, J. Oxley

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Aims: To assess the lymph node content of anterior prostatic fat (APF) sent routinely at robot-assisted laparoscopic radical prostatectomy (RALP) and the incidence of positive nodes in the extended pelvic lymph node dissection. Methods: Between September 2008 and April 2012, APF excised from 282 patients who underwent RALP was sent for pathological analysis. This tissue was completely embedded and lymph nodes counted. Results: In total, 49/282 (17%) patients had lymph nodes in the APF, median lymph node yield in this tissue was 1 (range 1-5). In four patients, the lymph nodes contained metastatic deposits. These patients did not have positive nodes elsewhere in the extended lymph node dissection. Conclusions: APF contains lymph nodes in 1 in 6 patients and infrequently these may be malignant. APF should always be removed at radical prostatectomy. APF should be routinely sent for pathological analysis.

Original language	English
Pages (from-to)	787-791
Number of pages	5
Journal	Journal of Clinical Pathology
Volume	67
Issue number	9
DOIs	https://doi.org/10.1136/jclinpath-2014-202303
Publication status	Published - Sept 2014
Externally published	Yes

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title = "Pathological analysis of lymph nodes in anterior prostatic fat excised at robot-assisted radical prostatectomy",

abstract = "Aims: To assess the lymph node content of anterior prostatic fat (APF) sent routinely at robot-assisted laparoscopic radical prostatectomy (RALP) and the incidence of positive nodes in the extended pelvic lymph node dissection. Methods: Between September 2008 and April 2012, APF excised from 282 patients who underwent RALP was sent for pathological analysis. This tissue was completely embedded and lymph nodes counted. Results: In total, 49/282 (17%) patients had lymph nodes in the APF, median lymph node yield in this tissue was 1 (range 1-5). In four patients, the lymph nodes contained metastatic deposits. These patients did not have positive nodes elsewhere in the extended lymph node dissection. Conclusions: APF contains lymph nodes in 1 in 6 patients and infrequently these may be malignant. APF should always be removed at radical prostatectomy. APF should be routinely sent for pathological analysis.",

author = "Aning, {Jonathan J.} and R. Thurairaja and Gillatt, {D. A.} and Koupparis, {A. J.} and Rowe, {E. W.} and J. Oxley",

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doi = "10.1136/jclinpath-2014-202303",

language = "English",

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journal = "Journal of Clinical Pathology",

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T1 - Pathological analysis of lymph nodes in anterior prostatic fat excised at robot-assisted radical prostatectomy

AU - Aning, Jonathan J.

AU - Thurairaja, R.

AU - Gillatt, D. A.

AU - Koupparis, A. J.

AU - Rowe, E. W.

AU - Oxley, J.

PY - 2014/9

Y1 - 2014/9

N2 - Aims: To assess the lymph node content of anterior prostatic fat (APF) sent routinely at robot-assisted laparoscopic radical prostatectomy (RALP) and the incidence of positive nodes in the extended pelvic lymph node dissection. Methods: Between September 2008 and April 2012, APF excised from 282 patients who underwent RALP was sent for pathological analysis. This tissue was completely embedded and lymph nodes counted. Results: In total, 49/282 (17%) patients had lymph nodes in the APF, median lymph node yield in this tissue was 1 (range 1-5). In four patients, the lymph nodes contained metastatic deposits. These patients did not have positive nodes elsewhere in the extended lymph node dissection. Conclusions: APF contains lymph nodes in 1 in 6 patients and infrequently these may be malignant. APF should always be removed at radical prostatectomy. APF should be routinely sent for pathological analysis.

AB - Aims: To assess the lymph node content of anterior prostatic fat (APF) sent routinely at robot-assisted laparoscopic radical prostatectomy (RALP) and the incidence of positive nodes in the extended pelvic lymph node dissection. Methods: Between September 2008 and April 2012, APF excised from 282 patients who underwent RALP was sent for pathological analysis. This tissue was completely embedded and lymph nodes counted. Results: In total, 49/282 (17%) patients had lymph nodes in the APF, median lymph node yield in this tissue was 1 (range 1-5). In four patients, the lymph nodes contained metastatic deposits. These patients did not have positive nodes elsewhere in the extended lymph node dissection. Conclusions: APF contains lymph nodes in 1 in 6 patients and infrequently these may be malignant. APF should always be removed at radical prostatectomy. APF should be routinely sent for pathological analysis.

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Pathological analysis of lymph nodes in anterior prostatic fat excised at robot-assisted radical prostatectomy

Abstract

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