TY - JOUR
T1 - Pathways of Pb and Mn observed in a 5-year longitudinal investigation in young children and environmental measures from an urban setting
AU - Gulson, Brian
AU - Mizon, Karen
AU - Taylor, Alan
AU - Korsch, Michael
AU - Davis, J. Michael
AU - Louie, Honway
AU - Wu, Michael
AU - Gomez, Laura
AU - Antin, Luminita
PY - 2014
Y1 - 2014
N2 - We monitored 108 children ≤5 years on a 6-month basis for up to 5 years in a major urban setting. Samples (n ∼ 7000) included blood, urine, handwipes (interior, and after exterior playing), 6-day duplicate diet, drinking water, interior house and day care dust-fall accumulation using petri dishes, exterior dust-fall accumulation, exterior dust sweepings, paint, soil and urban air. The geometric mean blood Pb (PbB) was 2.1 μg/dL and blood Mn (MnB) was 10.0 μg/L. Following a path modelling approach, mixed model analyses for a fully adjusted model showed the strongest associations for PbB were with interior house dust and soil; for MnB there were no significant associations with any predictors. Predictor variables only explained 9% of the variance for Pb and 0.7% for Mn. Relationships between environmental measures and PbB in children are not straightforward; soil and dust sweepings contribute only about 1/5th of the amounts to PbB found in other studies.
AB - We monitored 108 children ≤5 years on a 6-month basis for up to 5 years in a major urban setting. Samples (n ∼ 7000) included blood, urine, handwipes (interior, and after exterior playing), 6-day duplicate diet, drinking water, interior house and day care dust-fall accumulation using petri dishes, exterior dust-fall accumulation, exterior dust sweepings, paint, soil and urban air. The geometric mean blood Pb (PbB) was 2.1 μg/dL and blood Mn (MnB) was 10.0 μg/L. Following a path modelling approach, mixed model analyses for a fully adjusted model showed the strongest associations for PbB were with interior house dust and soil; for MnB there were no significant associations with any predictors. Predictor variables only explained 9% of the variance for Pb and 0.7% for Mn. Relationships between environmental measures and PbB in children are not straightforward; soil and dust sweepings contribute only about 1/5th of the amounts to PbB found in other studies.
UR - http://www.scopus.com/inward/record.url?scp=84899640172&partnerID=8YFLogxK
U2 - 10.1016/j.envpol.2014.04.009
DO - 10.1016/j.envpol.2014.04.009
M3 - Article
C2 - 24792883
AN - SCOPUS:84899640172
VL - 191
SP - 38
EP - 49
JO - Environmental Pollution
JF - Environmental Pollution
SN - 0269-7491
ER -