Patient reported outcomes of autologous fat grafting after breast cancer surgery

A. W.W. Brown, M. Kabir, K. A. Sherman, F. Meybodi, J. R. French, E. B. Elder

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Introduction: Autologous fat grafting (AFG) can be used as an adjunct in breast cancer surgery to improve contour defects. Few previous studies have assessed patient reported outcomes (PROs) for AFG. This study analysed AFG use and assessed PROs in terms of physical and psychosocial well-being. Materials and methods: All patients undergoing AFG were identified from a prospective database and asked to complete the validated BREAST-Q questionnaire and a tool to assess patient-perceived change after AFG (5-point Likert-type scale). Descriptive statistics were computed for all BREAST-Q and perceived change subscales. Independent sample t-tests were conducted to compare scores on each of the BREAST-Q and perceived change subscales by type of breast cancer surgery and radiotherapy status. Results: 156 AFG sessions were performed over 4 years on 119 breasts in 88 patients. Fifty-seven patients received AFG after reconstruction and 19 after breast conserving surgery. Forty-six patients (52%) completed the questionnaire. BREAST-Q scores (out of 100) and patient-perceived change after AFG (out of 5) were respectively: 54 and 4.0 for Breast satisfaction, 69 and 3.3 for Physical well-being and 60 and 3.6 for Psychosocial well-being. Radiotherapy status and type of surgery made little difference. Number of AFG procedures positively correlated with perceived improvement. Discussion: Autologous fat grafting was associated with improved patient satisfaction despite small volumes transferred. BREAST-Q scores were comparable with previously published series on reconstructive breast surgery. Perceived change after AFG was no different in patients receiving radiotherapy.

LanguageEnglish
Pages14-20
Number of pages7
JournalBreast
Volume35
DOIs
Publication statusPublished - Oct 2017
Externally publishedYes

Fingerprint

Fats
Breast Neoplasms
Breast
Radiotherapy
Reconstructive Surgical Procedures
Patient Reported Outcome Measures
Segmental Mastectomy
Patient Satisfaction
Databases

Keywords

  • patient reported outcome measures
  • breast cancer
  • breast reconstruction
  • lipofilling
  • fat grafting

Cite this

Brown, A. W.W. ; Kabir, M. ; Sherman, K. A. ; Meybodi, F. ; French, J. R. ; Elder, E. B. / Patient reported outcomes of autologous fat grafting after breast cancer surgery. In: Breast. 2017 ; Vol. 35. pp. 14-20.
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abstract = "Introduction: Autologous fat grafting (AFG) can be used as an adjunct in breast cancer surgery to improve contour defects. Few previous studies have assessed patient reported outcomes (PROs) for AFG. This study analysed AFG use and assessed PROs in terms of physical and psychosocial well-being. Materials and methods: All patients undergoing AFG were identified from a prospective database and asked to complete the validated BREAST-Q questionnaire and a tool to assess patient-perceived change after AFG (5-point Likert-type scale). Descriptive statistics were computed for all BREAST-Q and perceived change subscales. Independent sample t-tests were conducted to compare scores on each of the BREAST-Q and perceived change subscales by type of breast cancer surgery and radiotherapy status. Results: 156 AFG sessions were performed over 4 years on 119 breasts in 88 patients. Fifty-seven patients received AFG after reconstruction and 19 after breast conserving surgery. Forty-six patients (52{\%}) completed the questionnaire. BREAST-Q scores (out of 100) and patient-perceived change after AFG (out of 5) were respectively: 54 and 4.0 for Breast satisfaction, 69 and 3.3 for Physical well-being and 60 and 3.6 for Psychosocial well-being. Radiotherapy status and type of surgery made little difference. Number of AFG procedures positively correlated with perceived improvement. Discussion: Autologous fat grafting was associated with improved patient satisfaction despite small volumes transferred. BREAST-Q scores were comparable with previously published series on reconstructive breast surgery. Perceived change after AFG was no different in patients receiving radiotherapy.",
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Patient reported outcomes of autologous fat grafting after breast cancer surgery. / Brown, A. W.W.; Kabir, M.; Sherman, K. A.; Meybodi, F.; French, J. R.; Elder, E. B.

In: Breast, Vol. 35, 10.2017, p. 14-20.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Patient reported outcomes of autologous fat grafting after breast cancer surgery

AU - Brown, A. W.W.

AU - Kabir, M.

AU - Sherman, K. A.

AU - Meybodi, F.

AU - French, J. R.

AU - Elder, E. B.

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N2 - Introduction: Autologous fat grafting (AFG) can be used as an adjunct in breast cancer surgery to improve contour defects. Few previous studies have assessed patient reported outcomes (PROs) for AFG. This study analysed AFG use and assessed PROs in terms of physical and psychosocial well-being. Materials and methods: All patients undergoing AFG were identified from a prospective database and asked to complete the validated BREAST-Q questionnaire and a tool to assess patient-perceived change after AFG (5-point Likert-type scale). Descriptive statistics were computed for all BREAST-Q and perceived change subscales. Independent sample t-tests were conducted to compare scores on each of the BREAST-Q and perceived change subscales by type of breast cancer surgery and radiotherapy status. Results: 156 AFG sessions were performed over 4 years on 119 breasts in 88 patients. Fifty-seven patients received AFG after reconstruction and 19 after breast conserving surgery. Forty-six patients (52%) completed the questionnaire. BREAST-Q scores (out of 100) and patient-perceived change after AFG (out of 5) were respectively: 54 and 4.0 for Breast satisfaction, 69 and 3.3 for Physical well-being and 60 and 3.6 for Psychosocial well-being. Radiotherapy status and type of surgery made little difference. Number of AFG procedures positively correlated with perceived improvement. Discussion: Autologous fat grafting was associated with improved patient satisfaction despite small volumes transferred. BREAST-Q scores were comparable with previously published series on reconstructive breast surgery. Perceived change after AFG was no different in patients receiving radiotherapy.

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