TY - JOUR
T1 - pEl1573 Carrying bla(IMP-4), from Sydney, Australia, Is Closely Related to Other IncL/M Plasmids
AU - Partridge, Sally R.
AU - Ginn, Andrew N.
AU - Paulsen, Ian T.
AU - Iredell, Jonathan R.
PY - 2012/11
Y1 - 2012/11
N2 - Complete sequencing of pEl1573, a representative IncL/M plasmid carrying bla IMP- 4 from Sydney, Australia, revealed an ∼60-kb backbone almost identical to those of IncL/M plasmids pCTX-M3, from Poland, and pCTX-M360, from China, and less closely related to pNDM-HK, pOXA-48a, and pEL60, suggesting different lineages. The ∼28-kb Tn2-derived multiresistance region in pEl1573 is inserted in the same location as those in pCTX-M3 and pNDM-HK and shares some of the same components but has undergone rearrangements.
AB - Complete sequencing of pEl1573, a representative IncL/M plasmid carrying bla IMP- 4 from Sydney, Australia, revealed an ∼60-kb backbone almost identical to those of IncL/M plasmids pCTX-M3, from Poland, and pCTX-M360, from China, and less closely related to pNDM-HK, pOXA-48a, and pEL60, suggesting different lineages. The ∼28-kb Tn2-derived multiresistance region in pEl1573 is inserted in the same location as those in pCTX-M3 and pNDM-HK and shares some of the same components but has undergone rearrangements.
UR - http://www.scopus.com/inward/record.url?scp=84868033717&partnerID=8YFLogxK
U2 - 10.1128/AAC.01189-12
DO - 10.1128/AAC.01189-12
M3 - Article
C2 - 22926566
AN - SCOPUS:84868033717
SN - 0066-4804
VL - 56
SP - 6029
EP - 6032
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 11
ER -