Personality and neurochemicals in the human brain

A preliminary study using1H MRS

Shiyong Xu, Danling Peng*, Zhen Jin, Hongyan Liu, Jie Yang

*Corresponding author for this work

Research output: Contribution to journalArticle


To investigate the neuro-biological bases of introversion-extraversion personality traits, the concentration of four neurochemicals (Cho, mI, α-Glx and NAA) in anterior cigulate gyrus between normal extroverts and introverts were examined using non-invasive 1H MRS technique. Our study revealed that introverts have significantly higher level of α-Glx, Cho and mI in the anterior cingulate gyrus than extroverts. This result provides new evidence that the anterior cingulate gyrus is related to personality traits partly in support of Eysenck's supposition that introverts have higher arousal level than extroverts. Moreover, this result offers neurochemical data for psychobiological theories of personality.

Original languageEnglish
Pages (from-to)2318-2322
Number of pages5
JournalChinese Science Bulletin
Issue number20
Publication statusPublished - 2005


  • H MRS
  • Extraversion
  • Introversion
  • Neurochemical

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