Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines

Jiawen Li; Heike Ebendorff-Heidepriem; Brant C. Gibson; Andrew D. Greentree; Mark R. Hutchinson; Peipei Jia; Roman Kostecki; Guozhen Liu; Antony Orth; Martin Ploschner; Erik P. Schartner; Stephen C. Warren-Smith; Kaixin Zhang; Georgios Tsiminis; Ewa M. Goldys

doi:10.1063/1.5040861

Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines

Jiawen Li, Heike Ebendorff-Heidepriem, Brant C. Gibson, Andrew D. Greentree, Mark R. Hutchinson, Peipei Jia, Roman Kostecki, Guozhen Liu, Antony Orth, Martin Ploschner, Erik P. Schartner, Stephen C. Warren-Smith, Kaixin Zhang, Georgios Tsiminis, Ewa M. Goldys^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

The probing of physiological processes in living organisms is a grand challenge that requires bespoke analytical tools. Optical fiber probes offer a minimally invasive approach to report physiological signals from specific locations inside the body. This perspective article discusses a wide range of such fiber probes developed at the Australian Research Council Centre of Excellence for Nanoscale BioPhotonics. Our fiber platforms use a range of sensing modalities, including embedded nanodiamonds for magnetometry, interferometric fiber cavities for refractive index sensing, and tailored metal coatings for surface plasmon resonance sensing. Other fiber probes exploit molecularly sensitive Raman scattering or fluorescence where optical fibers have been combined with chemical and immunosensors. Fiber imaging probes based on interferometry and computational imaging are also discussed as emerging in vivo diagnostic devices. We provide examples to illustrate how the convergence of multiple scientific disciplines generates opportunities for the fiber probes to address key challenges in real-time in vivo diagnostics. These future fiber probes will enable the asking and answering of scientific questions that were never possible before.

Original language	English
Article number	100902
Pages (from-to)	1-21
Number of pages	21
Journal	APL Photonics
Volume	3
Issue number	10
DOIs	https://doi.org/10.1063/1.5040861
Publication status	Published - 1 Oct 2018

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Copyright Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

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Publisher version (open access)Final published version, 6.68 MBLicence: CC BY

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Li, J., Ebendorff-Heidepriem, H., Gibson, B. C., Greentree, A. D., Hutchinson, M. R., Jia, P., Kostecki, R., Liu, G., Orth, A., Ploschner, M., Schartner, E. P., Warren-Smith, S. C., Zhang, K., Tsiminis, G., & Goldys, E. M. (2018). Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines. APL Photonics, 3(10), 1-21. Article 100902. https://doi.org/10.1063/1.5040861

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title = "Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines",

abstract = "The probing of physiological processes in living organisms is a grand challenge that requires bespoke analytical tools. Optical fiber probes offer a minimally invasive approach to report physiological signals from specific locations inside the body. This perspective article discusses a wide range of such fiber probes developed at the Australian Research Council Centre of Excellence for Nanoscale BioPhotonics. Our fiber platforms use a range of sensing modalities, including embedded nanodiamonds for magnetometry, interferometric fiber cavities for refractive index sensing, and tailored metal coatings for surface plasmon resonance sensing. Other fiber probes exploit molecularly sensitive Raman scattering or fluorescence where optical fibers have been combined with chemical and immunosensors. Fiber imaging probes based on interferometry and computational imaging are also discussed as emerging in vivo diagnostic devices. We provide examples to illustrate how the convergence of multiple scientific disciplines generates opportunities for the fiber probes to address key challenges in real-time in vivo diagnostics. These future fiber probes will enable the asking and answering of scientific questions that were never possible before.",

author = "Jiawen Li and Heike Ebendorff-Heidepriem and Gibson, {Brant C.} and Greentree, {Andrew D.} and Hutchinson, {Mark R.} and Peipei Jia and Roman Kostecki and Guozhen Liu and Antony Orth and Martin Ploschner and Schartner, {Erik P.} and Warren-Smith, {Stephen C.} and Kaixin Zhang and Georgios Tsiminis and Goldys, {Ewa M.}",

note = "Copyright Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",

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Li, J, Ebendorff-Heidepriem, H, Gibson, BC, Greentree, AD, Hutchinson, MR, Jia, P, Kostecki, R, Liu, G, Orth, A, Ploschner, M, Schartner, EP, Warren-Smith, SC, Zhang, K, Tsiminis, G & Goldys, EM 2018, 'Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines', APL Photonics, vol. 3, no. 10, 100902, pp. 1-21. https://doi.org/10.1063/1.5040861

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Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines

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