Perspective

Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines

Jiawen Li, Heike Ebendorff-Heidepriem, Brant C. Gibson, Andrew D. Greentree, Mark R. Hutchinson, Peipei Jia, Roman Kostecki, Guozhen Liu, Antony Orth, Martin Ploschner, Erik P. Schartner, Stephen C. Warren-Smith, Kaixin Zhang, Georgios Tsiminis, Ewa M. Goldys*

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Citations (Scopus)
220 Downloads (Pure)

Abstract

The probing of physiological processes in living organisms is a grand challenge that requires bespoke analytical tools. Optical fiber probes offer a minimally invasive approach to report physiological signals from specific locations inside the body. This perspective article discusses a wide range of such fiber probes developed at the Australian Research Council Centre of Excellence for Nanoscale BioPhotonics. Our fiber platforms use a range of sensing modalities, including embedded nanodiamonds for magnetometry, interferometric fiber cavities for refractive index sensing, and tailored metal coatings for surface plasmon resonance sensing. Other fiber probes exploit molecularly sensitive Raman scattering or fluorescence where optical fibers have been combined with chemical and immunosensors. Fiber imaging probes based on interferometry and computational imaging are also discussed as emerging in vivo diagnostic devices. We provide examples to illustrate how the convergence of multiple scientific disciplines generates opportunities for the fiber probes to address key challenges in real-time in vivo diagnostics. These future fiber probes will enable the asking and answering of scientific questions that were never possible before.

Original languageEnglish
Article number100902
Pages (from-to)1-21
Number of pages21
JournalAPL photonics
Volume3
Issue number10
DOIs
Publication statusPublished - 1 Oct 2018

Bibliographical note

Copyright Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Fingerprint Dive into the research topics of 'Perspective: Biomedical sensing and imaging with optical fibers - Innovation through convergence of science disciplines'. Together they form a unique fingerprint.

Cite this