Pfeiffer syndrome

A clinical review

M. H. Moore*, S. B. Cantrell, J. A. Trott, D. J. David

*Corresponding author for this work

Research output: Contribution to journalReview article

44 Citations (Scopus)

Abstract

The combination of bicoronal craniosynostosis, broad thumbs and great toes, and partial variable soft tissue syndactyly of the hands and feet (i.e., Pfeiffer syndrome) classically followed a benign clinical course. A review of the clinical features of those Pfeiffer syndrome patients presenting to our unit confirm another subgroup in whom the craniofacial and associated manifestations are more extreme, with a significant risk of early demise. The early aggressive surgical management of craniostenosis, hydrocephalus, exorbitism, faciostenosis, and upper airway obstruction has provided the potential for prolonged useful survival in these cases.

Original languageEnglish
Pages (from-to)62-70
Number of pages9
JournalCleft Palate-Craniofacial Journal
Volume32
Issue number1
DOIs
Publication statusPublished - 1995
Externally publishedYes

Keywords

  • acrocephalosyndactyly
  • craniosynostosis
  • Pfeiffer syndrome

Fingerprint Dive into the research topics of 'Pfeiffer syndrome: A clinical review'. Together they form a unique fingerprint.

Cite this