Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn-3[Co(CN)(6)](2) nanocubes

Jian Chen, Mengni He, Pengping Xu, Huihui Wu, Zhen Guo*, Bingyang Shi, Qianwang Chen

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.

Original languageEnglish
Pages (from-to)84810-84814
Number of pages5
JournalRSC Advances
Volume6
Issue number88
DOIs
Publication statusPublished - 2016
Externally publishedYes

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