Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn-3[Co(CN)(6)](2) nanocubes

Jian Chen; Mengni He; Pengping Xu; Huihui Wu; Zhen Guo; Bingyang Shi; Qianwang Chen

doi:10.1039/c6ra08370f

Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn-3[Co(CN)(6)](2) nanocubes

Jian Chen, Mengni He, Pengping Xu, Huihui Wu, Zhen Guo^*, Bingyang Shi, Qianwang Chen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Luminescent Mn₃[Co(CN)₆]₂ nanocubes doped with Cd²⁺ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.

Original language	English
Pages (from-to)	84810-84814
Number of pages	5
Journal	RSC Advances
Volume	6
Issue number	88
DOIs	https://doi.org/10.1039/c6ra08370f
Publication status	Published - 2016
Externally published	Yes

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title = "Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn-3[Co(CN)(6)](2) nanocubes",

abstract = "Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.",

author = "Jian Chen and Mengni He and Pengping Xu and Huihui Wu and Zhen Guo and Bingyang Shi and Qianwang Chen",

year = "2016",

doi = "10.1039/c6ra08370f",

language = "English",

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pages = "84810--84814",

journal = "RSC Advances",

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T1 - Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn-3[Co(CN)(6)](2) nanocubes

AU - Chen, Jian

AU - He, Mengni

AU - Xu, Pengping

AU - Wu, Huihui

AU - Guo, Zhen

AU - Shi, Bingyang

AU - Chen, Qianwang

PY - 2016

Y1 - 2016

N2 - Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.

AB - Luminescent Mn3[Co(CN)6]2 nanocubes doped with Cd2+ can induce human lung adenocarcinoma cells A549 generating more metallothioneins (MTs) than squamous cells H520. The nanocubes can be bound to MTs and be excluded from cells for detoxification. Then A549 cells have a lower fluorescence imaging intensity than H520 cells, which can distinguish the two kinds of cells.

UR - http://www.scopus.com/inward/record.url?scp=84987619015&partnerID=8YFLogxK

U2 - 10.1039/c6ra08370f

DO - 10.1039/c6ra08370f

M3 - Article

AN - SCOPUS:84987619015

SN - 2046-2069

VL - 6

SP - 84810

EP - 84814

JO - RSC Advances

JF - RSC Advances

IS - 88

ER -

Photoluminescence distinction of lung adenocarcinoma cells A549 and squamous cells H520 using metallothionein expression in response to Cd-doped Mn-3[Co(CN)(6)](2) nanocubes

Abstract

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