Physiological responses of a rodent to heliox reveal constancy of evaporative water loss under perturbing environmental conditions

Christine Elizabeth Cooper*, Philip Carew Withers

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Total evaporative water loss of endotherms is assumed to be determined essentially by biophysics, at least at temperatures below thermoneutrality, with evaporative water loss determined by the water vapor deficit between the animal and the ambient air. We present here evidence, based on the first measurements of evaporative water loss for a small mammal in heliox, that mammals may have a previously unappreciated ability to maintain acute constancy of total evaporative water loss under perturbing environmental conditions. Thermoregulatory responses of ash-grey mice (Pseudomys albocinereus) to heliox were as expected, with changes in metabolic rate, conductance, and respiratory ventilation consistent with maintaining constancy of body temperature under conditions of enhanced heat loss. However, evaporative water loss did not increase in heliox. This is despite our confirmation of the physical effect that heliox augments evaporation from nonliving surfaces, which should increase cutaneous water loss, and increases minute volume of live ash-grey mice in heliox to accommodate their elevated metabolic rate, which should increase respiratory water loss. Therefore, mice had not only a thermoregulatory but also a hygroregulatory response to heliox. We interpret these results as evidence that ash-grey mice can acutely control their evaporative water loss under perturbing environmental conditions and suggest that hygroregulation at and below thermoneutrality is an important aspect of the physiology of at least some small mammals.

Original languageEnglish
Pages (from-to)R1042-R1048
Number of pages7
JournalAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
Volume307
Issue number8
DOIs
Publication statusPublished - 15 Oct 2014
Externally publishedYes

Keywords

  • ash grey mouse
  • endotherm
  • evaporative water loss
  • heliox
  • metabolic rate
  • regulation
  • ventilation
  • Metabolic rate
  • Ash grey mouse
  • Endotherm
  • Ventilation
  • Regulation
  • Evaporative water loss
  • Heliox

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