Phytochemical and antinociceptive study of leaves of Tabernaemontana divaricata (L)

Shazid Md. Sharker, Samabesh Chakma, Ahmed Ayedur Rahman

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The crude ethanol extract of leaves of Tabernaemontana divaricata (L). (Apocynaceae) was screened for its preliminary antinociceptive activity. The extract produced significant writhing inhibition in acetic acid induced mice at the oral dose of 250 and 500 mg/kg body weight respectively (P<0.05, P<0.01) comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. The result tends to suggest the antinociceptive activity of the extract.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalJournal of Medicinal Plants Research
Volume5
Issue number2
Publication statusPublished - 18 Jan 2011
Externally publishedYes

Keywords

  • Tabernaemontana divaricata
  • antinociceptive
  • writhing

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