pJIE137 carrying bla CTX-M-62 is closely related to p271A carrying bla NDM-1

Sally R. Partridge*, Ian T. Paulsen, Jonathan R. Iredell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Complete sequencing of pJIE137 revealed a backbone closely related to p271A, encoding a novel RepA protein but with a similar organization and up to ∼70% nucleotide identity to IncN plasmids. A region in pJIE137 resembling the IncN CUP regulon is mostly missing from p271A, presumably due to recombination. The class 1 In/Tn and ISEcp1-bla CTX-M-62 transposition unit in pJIE137 and a putative transposon carrying bla NDM-1 in p271A are inserted in different locations in the plasmid backbone.

Original languageEnglish
Pages (from-to)2166-2168
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume56
Issue number4
DOIs
Publication statusPublished - Apr 2012

Fingerprint

Dive into the research topics of 'pJIE137 carrying bla CTX-M-62 is closely related to p271A carrying bla NDM-1'. Together they form a unique fingerprint.

Cite this