pJIE137 carrying bla CTX-M-62 is closely related to p271A carrying bla NDM-1

Sally R. Partridge; Ian T. Paulsen; Jonathan R. Iredell

doi:10.1128/AAC.05796-11

pJIE137 carrying bla CTX-M-62 is closely related to p271A carrying bla NDM-1

Sally R. Partridge^*, Ian T. Paulsen, Jonathan R. Iredell

^*Corresponding author for this work

Macquarie University BioFocus Research Centre

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Complete sequencing of pJIE137 revealed a backbone closely related to p271A, encoding a novel RepA protein but with a similar organization and up to ∼70% nucleotide identity to IncN plasmids. A region in pJIE137 resembling the IncN CUP regulon is mostly missing from p271A, presumably due to recombination. The class 1 In/Tn and ISEcp1-bla _CTX-M-62 transposition unit in pJIE137 and a putative transposon carrying bla _NDM-1 in p271A are inserted in different locations in the plasmid backbone.

Original language	English
Pages (from-to)	2166-2168
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	56
Issue number	4
DOIs	https://doi.org/10.1128/AAC.05796-11
Publication status	Published - Apr 2012

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title = "pJIE137 carrying bla CTX-M-62 is closely related to p271A carrying bla NDM-1",

abstract = "Complete sequencing of pJIE137 revealed a backbone closely related to p271A, encoding a novel RepA protein but with a similar organization and up to ∼70% nucleotide identity to IncN plasmids. A region in pJIE137 resembling the IncN CUP regulon is mostly missing from p271A, presumably due to recombination. The class 1 In/Tn and ISEcp1-bla CTX-M-62 transposition unit in pJIE137 and a putative transposon carrying bla NDM-1 in p271A are inserted in different locations in the plasmid backbone.",

author = "Partridge, {Sally R.} and Paulsen, {Ian T.} and Iredell, {Jonathan R.}",

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AU - Paulsen, Ian T.

AU - Iredell, Jonathan R.

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AB - Complete sequencing of pJIE137 revealed a backbone closely related to p271A, encoding a novel RepA protein but with a similar organization and up to ∼70% nucleotide identity to IncN plasmids. A region in pJIE137 resembling the IncN CUP regulon is mostly missing from p271A, presumably due to recombination. The class 1 In/Tn and ISEcp1-bla CTX-M-62 transposition unit in pJIE137 and a putative transposon carrying bla NDM-1 in p271A are inserted in different locations in the plasmid backbone.

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SN - 0066-4804

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JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 4

ER -

pJIE137 carrying bla CTX-M-62 is closely related to p271A carrying bla NDM-1

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