Plasma testosterone levels and Δ5-3β-hydroxysteroid dehydrogenase activity in the testis of the rat following prolonged exposure to stress

I. Pollard; J. R. Bassett; J. M. P. Joss

doi:10.1530/jrf.0.0590101

Plasma testosterone levels and Δ⁵-3β-hydroxysteroid dehydrogenase activity in the testis of the rat following prolonged exposure to stress

I. Pollard, J. R. Bassett, J. M. P. Joss

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Exposure of male CSF rats to a signalled, unpredictable 60-day stress regimen induced a significant elevation in circulating testosterone levels at Days 1 and 60 which was abolished by castration. Small morphological changes were seen in the Leydig cells in the early days of stressing. A significant increase in 3β-HSD activity was seen by 5 days of stress, indicating increased steroidogenic activity.

Original language	English
Pages (from-to)	101-106
Number of pages	6
Journal	Journal of Reproduction and Fertility
Volume	59
Issue number	1
DOIs	https://doi.org/10.1530/jrf.0.0590101
Publication status	Published - 1980

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title = "Plasma testosterone levels and Δ5-3β-hydroxysteroid dehydrogenase activity in the testis of the rat following prolonged exposure to stress",

abstract = "Exposure of male CSF rats to a signalled, unpredictable 60-day stress regimen induced a significant elevation in circulating testosterone levels at Days 1 and 60 which was abolished by castration. Small morphological changes were seen in the Leydig cells in the early days of stressing. A significant increase in 3β-HSD activity was seen by 5 days of stress, indicating increased steroidogenic activity.",

author = "I. Pollard and Bassett, \{J. R.\} and Joss, \{J. M. P.\}",

year = "1980",

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T1 - Plasma testosterone levels and Δ5-3β-hydroxysteroid dehydrogenase activity in the testis of the rat following prolonged exposure to stress

AU - Pollard, I.

AU - Bassett, J. R.

AU - Joss, J. M. P.

PY - 1980

Y1 - 1980

N2 - Exposure of male CSF rats to a signalled, unpredictable 60-day stress regimen induced a significant elevation in circulating testosterone levels at Days 1 and 60 which was abolished by castration. Small morphological changes were seen in the Leydig cells in the early days of stressing. A significant increase in 3β-HSD activity was seen by 5 days of stress, indicating increased steroidogenic activity.

AB - Exposure of male CSF rats to a signalled, unpredictable 60-day stress regimen induced a significant elevation in circulating testosterone levels at Days 1 and 60 which was abolished by castration. Small morphological changes were seen in the Leydig cells in the early days of stressing. A significant increase in 3β-HSD activity was seen by 5 days of stress, indicating increased steroidogenic activity.

UR - https://www.scopus.com/pages/publications/0019224398

U2 - 10.1530/jrf.0.0590101

DO - 10.1530/jrf.0.0590101

M3 - Article

C2 - 6931229

AN - SCOPUS:0019224398

SN - 0022-4251

VL - 59

SP - 101

EP - 106

JO - Journal of Reproduction and Fertility

JF - Journal of Reproduction and Fertility

IS - 1

ER -

Plasma testosterone levels and Δ⁵-3β-hydroxysteroid dehydrogenase activity in the testis of the rat following prolonged exposure to stress

Abstract

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