Plasmonic nanostructures as surface-enhanced Raman scattering (SERS) substrate for protein biomarker sensing

Dan Li; Yuling Wang

doi:10.5772/intechopen.68164

Plasmonic nanostructures as surface-enhanced Raman scattering (SERS) substrate for protein biomarker sensing

Dan Li, Yuling Wang

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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Abstract

Plasmonic nanostructures have attracted considerable interest in biomarker sensing with the goal of rapid diagnostics and personalized nanomedicine. Surface‐enhanced Raman scattering (SERS) is a versatile technique for the characterization of the plasmonic effect of the metallic nanostructures as well as a sensitive read‐out approach for biomarkers detection. In this contribution, we will give a review on the key optical properties of plasmonic nanostructures as SERS substrate for protein biomarkers detection. As a consequence, two approaches, label‐free and SERS labels will be discussed in details for protein biomarkers sensing by using the plasmonic nanostructures as the substrate.

Original language	English
Title of host publication	Nanoplasmonics
Subtitle of host publication	fundamentals and applications
Editors	Grégory Barbillon
Publisher	InTechOpen
Chapter	15
Pages	341-359
Number of pages	19
ISBN (Electronic)	9789535147800
ISBN (Print)	9789535132783, 9789535132776
DOIs	https://doi.org/10.5772/intechopen.68164
Publication status	Published - 21 Jun 2017

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Copyright the Author(s) 2017. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

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Publisher version (open access)Final published version, 2.88 MBLicence: CC BY

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AB - Plasmonic nanostructures have attracted considerable interest in biomarker sensing with the goal of rapid diagnostics and personalized nanomedicine. Surface‐enhanced Raman scattering (SERS) is a versatile technique for the characterization of the plasmonic effect of the metallic nanostructures as well as a sensitive read‐out approach for biomarkers detection. In this contribution, we will give a review on the key optical properties of plasmonic nanostructures as SERS substrate for protein biomarkers detection. As a consequence, two approaches, label‐free and SERS labels will be discussed in details for protein biomarkers sensing by using the plasmonic nanostructures as the substrate.

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Plasmonic nanostructures as surface-enhanced Raman scattering (SERS) substrate for protein biomarker sensing

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