We report on the isolation of eight microsatellites from the sand tiger shark, Carcharias taurus, using an enrichment protocol. All loci, with the exception of Cta45-183, were in Hardy-Weinberg equilibrium. Loci exhibited three to 15 alleles, and observed and expected heterozygosities of 0.095-1.000 and 0.284-0.924, respectively. An additional marker (Iox-12) developed from a shortfin mako library was variable in sand tigers. These markers will be used to examine population genetics and mating patterns of this imperilled species.