Polypoid large intestinal involvement of metastatic castrate-resistant prostate cancer: a case report

Sathya Narayanan*, Sapir Dvuchbabny, Arteen Arzivian, Sang Kim, Robert Cheng, Howard Gurney

*Corresponding author for this work

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Abstract

Introduction: Prostate cancer most commonly metastasizes to the bone and lymph nodes. Gastrointestinal metastasis has been noted in the literature but appears to be an exceedingly uncommon phenomenon. Large intestinal involvement in particular has been reported on only a few occasions, and never concomitantly with small intestinal metastatic involvement. Case Report: We report the case of a 69-year-old gentleman with metastatic castrate-resistant prostate cancer with development of gastrointestinal symptomatology with extensive investigation eventually revealing small and large intestinal polyps subsequently confirmed to be representative of metastatic prostate cancer. Conclusion: This case demonstrates the importance of maintaining a wide differential diagnosis in the context of gastrointestinal symptomatology in malignancy. Thorough endoscopic evaluation may be necessary in such cases in order to identify potential metastatic malignancy in otherwise relatively unremarkable appearing polyps.

Original languageEnglish
Pages (from-to)717-724
Number of pages8
JournalCase Reports in Oncology
Volume17
Issue number1
DOIs
Publication statusPublished - 11 Jul 2024

Bibliographical note

Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • Castrate-resistant prostate cancer
  • Gastrointestinal bleeding
  • Gastrointestinal metastasis
  • Large intestinal polyps

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