Poor self-rated health is not associated with a high total allostatic load in type 2 diabetic patients - But high blood pressure is

A. C. Carlsson*, A. Nixon Andreasson, P. E. Wändell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Objective: Allostatic load has been linked to self-rated health (SRH), cardiovascular disease and mortality in non-diabetic individuals. The aim of this study was to construct an allostatic load score and to find any correlations with SRH. Methods: The subjects included in the study came from a randomized, controlled trial of type 2 diabetes. Blood samples were drawn, urine was collected for 24h, and questionnaires, including SRH, were filled out on three occasions: at baseline; after the 10-week intervention; and at a follow-up 3 months after the intervention. Allostatic load was estimated using a wide range of variables, including systolic and diastolic blood pressure, pulse pressure, cortisol, catecholamines, HbA 1c, insulin, plasma glucose and waist circumference. Results: There was no association between SRH and allostatic load. However, three other components were significantly correlated with allostatic load at the baseline investigation and the two follow-up investigations - namely, systolic blood pressure, diastolic blood pressure and HbA 1c. Conclusion: The absence of an association between allostatic load and SRH in diabetic individuals contrasts with previous findings in non-diabetic women, and shows that it is hazardous to apply findings in one population to another, especially diabetic and non-diabetic populations.

Original languageEnglish
Pages (from-to)446-451
Number of pages6
JournalDiabetes and Metabolism
Volume37
Issue number5
DOIs
Publication statusPublished - Nov 2011
Externally publishedYes

Keywords

  • Allostatic load
  • Blood pressure
  • Cardiovascular prevention
  • Diabetes
  • Self-rated health

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