Potential injectable contraceptive steroids: Testosterone buciclate

Nathaniel W. Alcock*, Karen J. Sanders, Alison Rodger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis of buciclate ester of testosterone, C30H 46O3, as a part of World Health Organization's programme for the development of injectable contraceptive steroids, was analyzed. The aim of the program was to develop long-acting injectable steroids for both men and women that retained an approximately constant pharmacokinetic profile. The steroid synthesis programme focused on making new esters, oximes and ethers of steroids with known contraceptive activity. The crystal structure and conformation of the steroid was the same as expected to be.

Original languageEnglish
Article numberE60
Pages (from-to)o348-sup7
Number of pages9
JournalActa Crystallographica Section E: Structure Reports Online
Volume60
Issue number3
DOIs
Publication statusPublished - Mar 2004
Externally publishedYes

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