Predictors of outcome three years after diagnosis of first episode psychosis

Sara Lucas*, Marie Antoinette Redoblado-Hodge, Arthur Shores, John Brennan, Anthony Harris

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    17 Citations (Scopus)


    This study aimed to determine which of demographic/premorbid, psychiatric or neuropsychological factors best predict functional outcome at 3 years after a first episode of psychotic illness. This will, it is hoped, identify prognostic indicators of longer term outcomes, as well as targets for rehabilitation. The Western Sydney First Episode Psychosis Project collected data on young people (aged 13 to 25) presenting with newly diagnosed psychosis at baseline and 3-year follow-up (n = 52). Outcome was measured using the Role Functioning Scale (RFS) and the Clinical Global Impression Scale - severity of illness measure (CGI-S). Multiple regression analyses were performed to identify baseline predictors of outcome. The Premorbid Social Adjustment Scale in Adolescence (PSAS-Adolescent) and the Verbal Comprehension Index from the WAIS-III were found to be the two significant predictors for RFS, with only the former (PSAS-Adolescent) predicting CGI-S. Demographic and neuropsychological measures relating to premorbid functioning were the best predictors of long-term outcome in first episode psychosis, with baseline psychiatric symptoms not contributing. Crown

    Original languageEnglish
    Pages (from-to)11-18
    Number of pages8
    JournalPsychiatry Research
    Issue number1
    Publication statusPublished - 30 Oct 2008


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