Preliminary safety and efficacy of Bgb-11417, a novel Bcl-2 inhibitor, in combination with azacitidine in patients with acute myeloid leukemia (AML)

Jake Shortt; Pau Montesinos; Shuh Ying Tan; Teng Fong Ng; Chun Yew Fong; Paul Cannell; Rajeev Rajagopal; Sophia Leitch; Peter T. Tan; Sundra Ramanathan; Robin Gasiorowski; Douglas Stuart Lenton; Tse-Chieh Teh; Jose Antonio Perez-Simon; Carolyn Grove; Xiaojun Huang; Courtney D. DiNardo; Katherine Naidu; Joseph Pariseau; Si Cheng; Yu Liu; Melannie Co; Wai Y. Chan; Haiyi Guo; Andrew H. Wei

doi:10.1182/blood-2022-166937

Preliminary safety and efficacy of Bgb-11417, a novel Bcl-2 inhibitor, in combination with azacitidine in patients with acute myeloid leukemia (AML)

Jake Shortt, Pau Montesinos, Shuh Ying Tan, Teng Fong Ng, Chun Yew Fong, Paul Cannell, Rajeev Rajagopal, Sophia Leitch, Peter T. Tan, Sundra Ramanathan, Robin Gasiorowski, Douglas Stuart Lenton, Tse-Chieh Teh, Jose Antonio Perez-Simon, Carolyn Grove, Xiaojun Huang, Courtney D. DiNardo, Katherine Naidu, Joseph Pariseau, Si ChengYu Liu, Melannie Co, Wai Y. Chan, Haiyi Guo, Andrew H. Wei

Research output: Contribution to journal › Meeting abstract › peer-review

Original language	English
Pages (from-to)	3329-3332
Number of pages	4
Journal	Blood
Volume	140
Issue number	Supplement 1
DOIs	https://doi.org/10.1182/blood-2022-166937
Publication status	Published - 15 Nov 2022
Externally published	Yes
Event	64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH) - New Orleans, United States Duration: 10 Dec 2022 → 13 Dec 2022

Access to Document

10.1182/blood-2022-166937

Cite this

Shortt, J., Montesinos, P., Tan, S. Y., Ng, T. F., Fong, C. Y., Cannell, P., Rajagopal, R., Leitch, S., Tan, P. T., Ramanathan, S., Gasiorowski, R., Lenton, D. S., Teh, T.-C., Perez-Simon, J. A., Grove, C., Huang, X., DiNardo, C. D., Naidu, K., Pariseau, J., ... Wei, A. H. (2022). Preliminary safety and efficacy of Bgb-11417, a novel Bcl-2 inhibitor, in combination with azacitidine in patients with acute myeloid leukemia (AML). Blood, 140(Supplement 1), 3329-3332. https://doi.org/10.1182/blood-2022-166937

@article{257fb5a8c43344ecb9515632f8a07b70,

title = "Preliminary safety and efficacy of Bgb-11417, a novel Bcl-2 inhibitor, in combination with azacitidine in patients with acute myeloid leukemia (AML)",

author = "Jake Shortt and Pau Montesinos and Tan, \{Shuh Ying\} and Ng, \{Teng Fong\} and Fong, \{Chun Yew\} and Paul Cannell and Rajeev Rajagopal and Sophia Leitch and Tan, \{Peter T.\} and Sundra Ramanathan and Robin Gasiorowski and Lenton, \{Douglas Stuart\} and Tse-Chieh Teh and Perez-Simon, \{Jose Antonio\} and Carolyn Grove and Xiaojun Huang and DiNardo, \{Courtney D.\} and Katherine Naidu and Joseph Pariseau and Si Cheng and Yu Liu and Melannie Co and Chan, \{Wai Y.\} and Haiyi Guo and Wei, \{Andrew H.\}",

year = "2022",

month = nov,

day = "15",

doi = "10.1182/blood-2022-166937",

language = "English",

volume = "140",

pages = "3329--3332",

journal = "Blood",

issn = "0006-4971",

publisher = "Elsevier",

number = "Supplement 1",

note = "64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH) ; Conference date: 10-12-2022 Through 13-12-2022",

}

Shortt, J, Montesinos, P, Tan, SY, Ng, TF, Fong, CY, Cannell, P, Rajagopal, R, Leitch, S, Tan, PT, Ramanathan, S, Gasiorowski, R, Lenton, DS, Teh, T-C, Perez-Simon, JA, Grove, C, Huang, X, DiNardo, CD, Naidu, K, Pariseau, J, Cheng, S, Liu, Y, Co, M, Chan, WY, Guo, H & Wei, AH 2022, 'Preliminary safety and efficacy of Bgb-11417, a novel Bcl-2 inhibitor, in combination with azacitidine in patients with acute myeloid leukemia (AML)', Blood, vol. 140, no. Supplement 1, pp. 3329-3332. https://doi.org/10.1182/blood-2022-166937

TY - JOUR

T1 - Preliminary safety and efficacy of Bgb-11417, a novel Bcl-2 inhibitor, in combination with azacitidine in patients with acute myeloid leukemia (AML)

AU - Shortt, Jake

AU - Montesinos, Pau

AU - Tan, Shuh Ying

AU - Ng, Teng Fong

AU - Fong, Chun Yew

AU - Cannell, Paul

AU - Rajagopal, Rajeev

AU - Leitch, Sophia

AU - Tan, Peter T.

AU - Ramanathan, Sundra

AU - Gasiorowski, Robin

AU - Lenton, Douglas Stuart

AU - Teh, Tse-Chieh

AU - Perez-Simon, Jose Antonio

AU - Grove, Carolyn

AU - Huang, Xiaojun

AU - DiNardo, Courtney D.

AU - Naidu, Katherine

AU - Pariseau, Joseph

AU - Cheng, Si

AU - Liu, Yu

AU - Co, Melannie

AU - Chan, Wai Y.

AU - Guo, Haiyi

AU - Wei, Andrew H.

PY - 2022/11/15

Y1 - 2022/11/15

U2 - 10.1182/blood-2022-166937

DO - 10.1182/blood-2022-166937

M3 - Meeting abstract

SN - 0006-4971

VL - 140

SP - 3329

EP - 3332

JO - Blood

JF - Blood

IS - Supplement 1

T2 - 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)

Y2 - 10 December 2022 through 13 December 2022

ER -