Preparation of DNA-silver nanohybrids in multilayer nanoreactors by in situ electrochemical reduction, characterization, and application

Li Shang, Yuling Wang, Lijian Huang, Shaojun Dong*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)

Abstract

Novel nanocomposite films containing DNA-silver nanohybrids have been successfully fabricated by combined use of die layer-by-layer self-assembly technique and an in situ electrochemical reduction method widi the DNA-Ag + complex as one of the building blocks. UV-vis absorption spectroscopy was employed to monitor the buildup of die multilayer films, which suggested a progressive deposition widi almost an equal amount of the DNA-Ag+ complex in each cycle. The following electrochemical reduction of silver resulted in the formation of metal nanoparticles in the film, which was evidenced by die evolution of die intense plasmon absorption band originating from silver. Scanning electron microscopy indicated that die particles formed in the multilayer films possessed good monodispersity and stability, thanks to die surrounding polymers. X-ray photoelectron spectroscopy further confirmed die presence of the main components (such as DNA and metallic silver) of the nanocomposite films. In addition, we show that the size of the metal nanoparticles and the optical property of the film could be readily tuned by manipulating the assembly conditions. Furthermore, the feasibility of the as-prepared nanocomposite films functioning as a surfaceenhanced Raman scattering active substrate for sensing purposes was investigated, and die results showed great enhancement of die Raman signal of two probe molecules, Rhodamine 6G and 4-aminothiophenol.

Original languageEnglish
Pages (from-to)7738-7744
Number of pages7
JournalLangmuir
Volume23
Issue number14
DOIs
Publication statusPublished - 3 Jul 2007
Externally publishedYes

Fingerprint Dive into the research topics of 'Preparation of DNA-silver nanohybrids in multilayer nanoreactors by in situ electrochemical reduction, characterization, and application'. Together they form a unique fingerprint.

Cite this