Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

Theodorus Van Es; Benjamin Staskun; Manuel A. Fernandes

doi:10.3184/030823407X225392

Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

Theodorus Van Es, Benjamin Staskun^*, Manuel A. Fernandes

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

Original language	English
Pages (from-to)	373-376
Number of pages	4
Journal	Journal of Chemical Research
Issue number	6
DOIs	https://doi.org/10.3184/030823407X225392
Publication status	Published - Jun 2007

Access to Document

10.3184/030823407X225392

Cite this

@article{8afec71c5d894db29710c1e8ebdd3bde,

title = "Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one",

abstract = "Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.",

author = "{Van Es}, Theodorus and Benjamin Staskun and Fernandes, {Manuel A.}",

year = "2007",

month = jun,

doi = "10.3184/030823407X225392",

language = "English",

pages = "373--376",

journal = "Journal of Chemical Research",

issn = "0308-2342",

publisher = "Science Reviews Ltd",

number = "6",

}

TY - JOUR

T1 - Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

AU - Van Es, Theodorus

AU - Staskun, Benjamin

AU - Fernandes, Manuel A.

PY - 2007/6

Y1 - 2007/6

N2 - Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

AB - Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

UR - http://www.scopus.com/inward/record.url?scp=34547777366&partnerID=8YFLogxK

U2 - 10.3184/030823407X225392

DO - 10.3184/030823407X225392

M3 - Article

AN - SCOPUS:34547777366

SN - 0308-2342

SP - 373

EP - 376

JO - Journal of Chemical Research

JF - Journal of Chemical Research

IS - 6

ER -

Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

Abstract

Access to Document

Other files and links

Fingerprint

Cite this