Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

Theodorus Van Es; Benjamin Staskun; Manuel A. Fernandes

doi:10.3184/030823407X225392

Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

Theodorus Van Es, Benjamin Staskun^*, Manuel A. Fernandes

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

Original language	English
Pages (from-to)	373-376
Number of pages	4
Journal	Journal of Chemical Research
Issue number	6
DOIs	https://doi.org/10.3184/030823407X225392
Publication status	Published - Jun 2007

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title = "Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one",

abstract = "Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50\%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.",

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year = "2007",

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AU - Van Es, Theodorus

AU - Staskun, Benjamin

AU - Fernandes, Manuel A.

PY - 2007/6

Y1 - 2007/6

N2 - Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

AB - Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

UR - https://www.scopus.com/pages/publications/34547777366

U2 - 10.3184/030823407X225392

DO - 10.3184/030823407X225392

M3 - Article

AN - SCOPUS:34547777366

SN - 0308-2342

SP - 373

EP - 376

JO - Journal of Chemical Research

JF - Journal of Chemical Research

IS - 6

ER -

Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7- dihydro-thieno[3,4-b]pyridin-5-one

Abstract

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