Presumed choroidal metastasis from soft tissue myoepithelial carcinoma

Michelle M. Hui, Rohan Merani, Fiona Bonar, Angela M. Hong, Adrian T. Fung*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)
    35 Downloads (Pure)

    Abstract

    Purpose: To report a case of presumed choroidal metastasis from soft tissue myoepithelial carcinoma and highlight challenges in its diagnosis. Observations: A 52-year-old man was referred with a two-week history of photopsia in his left eye. His background medical history included known soft tissue myoepithelial carcinoma metastatic to his bone, lung, liver and chest wall. A large, raised, yellow choroidal lesion was identified nasal to and abutting the optic disc. This lesion demonstrated growth 1 month after presentation. The patient died with widespread metastatic disease 5 months after initial presentation. Conclusion and importance: Soft tissue myoepithelial carcinoma can rarely metastasise to the choroid and present as a rapidly-growing, yellow, echodense tumour with serous retinal detachment. MRI brain can assist in tumour evaluation and monitoring progression, while immunoperoxidase stains and molecular testing can assist with diagnosis. The condition has an aggressive natural history and poor prognosis.

    Original languageEnglish
    Pages (from-to)55-57
    Number of pages3
    JournalAmerican Journal of Ophthalmology Case Reports
    Volume14
    DOIs
    Publication statusPublished - 1 Jun 2019

    Bibliographical note

    Copyright the Author(s) 2019. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

    Keywords

    • Choroid
    • Choroidal metastases
    • Myoepithelioma
    • Myoepithelioma carcinoma
    • Oncology
    • Soft tissue myoepithelioma

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