Prevalence and predictors of poor sleep quality in mild cognitive impairment

Andrew McKinnon, Zoe Terpening, Ian B. Hickie, Jennifer Batchelor, Ron Grunstein, Simon J G Lewis, Sharon L. Naismith*

*Corresponding author for this work

    Research output: Contribution to journalArticle

    31 Citations (Scopus)


    Aims: To investigate the prevalence of and contributors to poor sleep quality in patients with mild cognitive impairment (MCI). Methods: Data were collected for 158 patients meeting the criteria for MCI. Measures included the Pittsburgh Sleep Quality Index, Geriatric Depression Scale, and Mini-Mental State Examination. Demographic, lifestyle, medication, and substance use data were also collected. Results: A total of 63% of patients with MCI demonstrated sleep disturbance, a significantly higher rate than that of the controls (44%; chi-square = 8.77; P = .003). Depressive symptoms, cognition, antidepressant usage, alcohol consumption, age, and education were identified as significant predictors of self-reported sleep quality in patients with MCI (R2 = .327, F6,145 = 11.729, P < .0001). Conclusions: Sleep disturbance occurs in around two-thirds of patients with MCI. Interventions addressing depression, cognition, and substance and medication use may improve sleep quality in MCI.

    Original languageEnglish
    Pages (from-to)204-211
    Number of pages8
    JournalJournal of Geriatric Psychiatry and Neurology
    Issue number3
    Publication statusPublished - 1 Sep 2014


    • depression
    • mild cognitive impairment
    • sleep disturbance
    • sleep quality

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