TY - JOUR
T1 - Prevalence and predictors of poor sleep quality in mild cognitive impairment
AU - McKinnon, Andrew
AU - Terpening, Zoe
AU - Hickie, Ian B.
AU - Batchelor, Jennifer
AU - Grunstein, Ron
AU - Lewis, Simon J G
AU - Naismith, Sharon L.
PY - 2014/9/1
Y1 - 2014/9/1
N2 - Aims: To investigate the prevalence of and contributors to poor sleep quality in patients with mild cognitive impairment (MCI). Methods: Data were collected for 158 patients meeting the criteria for MCI. Measures included the Pittsburgh Sleep Quality Index, Geriatric Depression Scale, and Mini-Mental State Examination. Demographic, lifestyle, medication, and substance use data were also collected. Results: A total of 63% of patients with MCI demonstrated sleep disturbance, a significantly higher rate than that of the controls (44%; chi-square = 8.77; P = .003). Depressive symptoms, cognition, antidepressant usage, alcohol consumption, age, and education were identified as significant predictors of self-reported sleep quality in patients with MCI (R2 = .327, F6,145 = 11.729, P < .0001). Conclusions: Sleep disturbance occurs in around two-thirds of patients with MCI. Interventions addressing depression, cognition, and substance and medication use may improve sleep quality in MCI.
AB - Aims: To investigate the prevalence of and contributors to poor sleep quality in patients with mild cognitive impairment (MCI). Methods: Data were collected for 158 patients meeting the criteria for MCI. Measures included the Pittsburgh Sleep Quality Index, Geriatric Depression Scale, and Mini-Mental State Examination. Demographic, lifestyle, medication, and substance use data were also collected. Results: A total of 63% of patients with MCI demonstrated sleep disturbance, a significantly higher rate than that of the controls (44%; chi-square = 8.77; P = .003). Depressive symptoms, cognition, antidepressant usage, alcohol consumption, age, and education were identified as significant predictors of self-reported sleep quality in patients with MCI (R2 = .327, F6,145 = 11.729, P < .0001). Conclusions: Sleep disturbance occurs in around two-thirds of patients with MCI. Interventions addressing depression, cognition, and substance and medication use may improve sleep quality in MCI.
KW - depression
KW - mild cognitive impairment
KW - sleep disturbance
KW - sleep quality
UR - http://www.scopus.com/inward/record.url?scp=84907210871&partnerID=8YFLogxK
U2 - 10.1177/0891988714527516
DO - 10.1177/0891988714527516
M3 - Article
C2 - 24687189
AN - SCOPUS:84907210871
SN - 0891-9887
VL - 27
SP - 204
EP - 211
JO - Journal of Geriatric Psychiatry and Neurology
JF - Journal of Geriatric Psychiatry and Neurology
IS - 3
ER -