TY - JOUR
T1 - Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study
T2 - a multinational cross-sectional study
AU - Abozid, Hazim
AU - Patel, Jaymini
AU - Burney, Peter
AU - Hartl, Sylvia
AU - Breyer-Kohansal, Robab
AU - Mortimer, Kevin
AU - Nafees, Asaad A.
AU - Al Ghobain, Mohammed
AU - Welte, Tobias
AU - Harrabi, Imed
AU - Denguezli, Meriam
AU - Loh, Li Cher
AU - Rashid, Abdul
AU - Gislason, Thorarinn
AU - Barbara, Cristina
AU - Cardoso, Joao
AU - Rodrigues, Fatima
AU - Seemungal, Terence
AU - Obaseki, Daniel
AU - Juvekar, Sanjay
AU - Paraguas, Stefanni Nonna
AU - Tan, Wan C.
AU - Franssen, Frits M. E.
AU - Mejza, Filip
AU - Mannino, David
AU - Janson, Christer
AU - Cherkaski, Hamid Hacene
AU - Anand, Mahesh Padukudru
AU - Hafizi, Hasan
AU - Buist, Sonia
AU - Koul, Parvaiz A.
AU - Elsony, Asma
AU - Breyer, Marie Kathrin
AU - Burghuber, Otto C.
AU - Wouters, E. F. M.
AU - Amaral, Andre F. S.
AU - BOLD Collaborative Research Group
AU - Aliko, Anila
AU - Bardhi, Donika
AU - Tafa, Holta
AU - Thanasi, Natasha
AU - Mezini, Arian
AU - Teferici, Alma
AU - Todri, Dafina
AU - Nikolla, Jolanda
AU - Kazasi, Rezarta
AU - Bengrait, Amira
AU - Haddad, Tabarek
AU - Zgaoula, Ibtissem
AU - Ghit, Maamar
AU - Roubhia, Abdelhamid
AU - Boudra, Soumaya
AU - Atoui, Feryal
AU - Yakoubi, Randa
AU - Benali, Rachid
AU - Bencheikh, Abdelghani
AU - Ait-Khaled, Nadia
AU - Jenkins, Christine
AU - Marks, Guy
AU - Bird, Tessa
AU - Espinel, Paola
AU - Hardaker, Kate
AU - Toelle, Brett
AU - Studnicka, Michael
AU - Dawes, Torkil
AU - Lamprecht, Bernd
AU - Schirhofer, Lea
AU - Islam, Akramul
AU - Ahmed, Syed Masud
AU - Islam, Shayla
AU - Islam, Qazi Shafayetul
AU - Mesbah-Ul-Haque,
AU - Chowdhury, Tridib Roy
AU - Chatterjee, Sukantha Kumar
AU - Mia, Dulal
AU - Chandra Das, Shyamal
AU - Rahman, Mizanur
AU - Islam, Nazrul
AU - Uddin, Shahaz
AU - Islam, Nurul
AU - Khatun, Luiza
AU - Parvin, Monira
AU - Khan, Abdul Awal
AU - Islam, Maidul
AU - Lawin, Herve
AU - Kpangon, Arsene
AU - Kpossou, Karl
AU - Agodokpessi, Gildas
AU - Ayelo, Paul
AU - Fayomi, Benjamin
AU - Mbatchou, Bertrand
AU - Ashu, Atongno Humphrey
AU - Wang, Wen
AU - Zhong, Nan Shan
AU - Liu, Shengming
AU - Lu, Jiachun
AU - Ran, Pixin
AU - Wang, Dali
AU - Zheng, Jin ping
AU - Zhou, Yumin
AU - Jogi, Rain
AU - Laja, Hendrik
AU - Ulst, Katrin
AU - Zobel, Vappu
AU - Lill, Toomas Julius
AU - Adegnika, Ayola Akim
AU - Bodemann, Isabelle
AU - Geldmacher, Henning
AU - SchwedaLinow, Alexandra
AU - Benedikdtsdottir, Bryndis
AU - Jorundsdottir, Kristin
AU - Lovisa Gudmundsdottir, Gudmundsdottir
AU - Gudmundsdottir, Sigrun
AU - Gudmundsson, Gunnar
AU - Rao, Mahesh
AU - Malik, Sajjad
AU - Hakim, Nissar A.
AU - Khan, Umar Hafiz
AU - Chowgule, Rohini
AU - Shetye, Vasant
AU - Raphael, Jonelle
AU - Almeda, Rosel
AU - Tawde, Mahesh
AU - Tadvi, Rafiq
AU - Katkar, Sunil
AU - Kadam, Milind
AU - Dhanawade, Rupesh
AU - Ghurup, Umesh
AU - Hirve, Siddhi
AU - Sambhudas, Somnath
AU - Chaidhary, Bharat
AU - Tambe, Meera
AU - Pingale, Savita
AU - Umap, Arati
AU - Umap, Archana
AU - Shelar, Nitin
AU - Devchakke, Sampada
AU - Chaudhary, Sharda
AU - Bondre, Suvarna
AU - Walke, Savita
AU - Gawhane, Ashleshsa
AU - Sapkal, Anil
AU - Argade, Rupali
AU - Gaikwad, Vijay
AU - Salvi, Sundeep
AU - Brashier, Bill
AU - Londhe, Jyoti
AU - Madas, Sapna
AU - Aquart-Stewart, Althea
AU - Aikman, Akosua Francia
AU - Sooronbaev, Talant M.
AU - Estebesova, Bermet M.
AU - Akmatalieva, Meerim
AU - Usenbaeva, Saadat
AU - Kydyrova, Jypara
AU - Bostonova, Eliza
AU - Sheraliev, Ulan
AU - Marajapov, Nuridin
AU - Toktogulova, Nurgul
AU - Emilov, Berik
AU - Azilova, Toktogul
AU - Beishekeeva, Gulnara
AU - Dononbaeva, Nasyikat
AU - Tabyshova, Aijamal
AU - Nyapigoti, Wezzie
AU - Mwangoka, Ernest
AU - Kambwili, Mayamiko
AU - Chipeta, Martha
AU - Banda, Gloria
AU - Mkandawire, Suzgo
AU - Banda, Justice
AU - Loh, Li Cher
AU - Sholehah, Siti
AU - Benjelloun, Mohamed C.
AU - Nejjari, Chakib
AU - Elbiaze, Mohamed
AU - El Rhazi, Karima
AU - Wouters, E. F.M.
AU - Wesseling, G. J.
AU - Erhabor, Gregory
AU - Awopeju, Olayemi
AU - Adewole, Olufemi
AU - Gulsvik, Amund
AU - Endresen, Tina
AU - Svendsen, Lene
AU - Irfan, Muhammad
AU - Fatmi, Zafar
AU - Zahidie, Aysha
AU - Shaukat, Natasha
AU - Iqbal, Meesha
AU - Idolor, Luisito F.
AU - de Guia, Teresita S.
AU - Francisco, Norberto A.
AU - Roa, Camilo C.
AU - Ayuyao, Fernando G.
AU - Tady, Cecil Z.
AU - Tan, Daniel T.
AU - Banal-Yang, Sylvia
AU - Balanag, Vincent M.
AU - Reyes, Maria Teresita N.
AU - Dantes, Renato B.
AU - Amarillo, Lourdes
AU - Berratio, Lakan U.
AU - Fernandez, Lenora C.
AU - Garcia, Gerard S.
AU - Naval, Sullian S.
AU - Reyes, Thessa
AU - Sanchez, Flordeliza
AU - Simpao, Leander P.
AU - Nizankowska-Mogilnicka, Ewa
AU - Frey, Jakub
AU - Harat, Rafal
AU - Nastalek, Pawel
AU - Pajak, Andrzej
AU - Skucha, Wojciech
AU - Szczeklik, Andrzej
AU - Twardowska, Magda
AU - Dias, Herminia
AU - Almeida, João
AU - Matos, Maria Joao
AU - Simão, Paula
AU - Santos, Moutinho
AU - Ferreira, Reis
AU - Al Ghobain, M.
AU - Alorainy, H.
AU - El-Hamad, E.
AU - Al Hajjaj, M.
AU - Hashi, A.
AU - Dela, R.
AU - Fanuncio, R.
AU - Doloriel, E.
AU - Marciano, I.
AU - Safia, L.
AU - Bateman, Eric
AU - Jithoo, Anamika
AU - Adams, Desiree
AU - Barnes, Edward
AU - Freeman, Jasper
AU - Hayes, Anton
AU - Hlengwa, Sipho
AU - Johannisen, Christine
AU - Koopman, Mariana
AU - Louw, Innocentia
AU - Ludick, Ina
AU - Olckers, Alta
AU - Ryck, Johanna
AU - Storbeck, Janita
AU - Gunasekera, Kirthi
AU - Wickremasinghe, Rajitha
AU - Elsony, Asma
AU - Elsadig, Hana A.
N1 - Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
PY - 2024/2
Y1 - 2024/2
N2 - Background: Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a standardised protocol and definition. Methods: We analysed cross-sectional data from 33,983 adults (≥40 years), recruited between Jan 2, 2003 and Dec 26, 2016, in 41 sites (34 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We estimated the prevalence of chronic cough for each site accounting for sampling design. To identify risk factors, we conducted multivariable logistic regression analysis within each site and then pooled estimates using random-effects meta-analysis. We also calculated the population attributable risk (PAR) associated with each of the identifed risk factors. Findings: The prevalence of chronic cough varied from 3% in India (rural Pune) to 24% in the United States of America (Lexington,KY). Chronic cough was more common among females, both current and passive smokers, those working in a dusty job, those with a history of tuberculosis, those who were obese, those with a low level of education and those with hypertension or airflow limitation. The most influential risk factors were current smoking and working in a dusty job. Interpretation: Our findings suggested that the prevalence of chronic cough varies widely across sites in different world regions. Cigarette smoking and exposure to dust in the workplace are its major risk factors. Funding: Wellcome Trust.
AB - Background: Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a standardised protocol and definition. Methods: We analysed cross-sectional data from 33,983 adults (≥40 years), recruited between Jan 2, 2003 and Dec 26, 2016, in 41 sites (34 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We estimated the prevalence of chronic cough for each site accounting for sampling design. To identify risk factors, we conducted multivariable logistic regression analysis within each site and then pooled estimates using random-effects meta-analysis. We also calculated the population attributable risk (PAR) associated with each of the identifed risk factors. Findings: The prevalence of chronic cough varied from 3% in India (rural Pune) to 24% in the United States of America (Lexington,KY). Chronic cough was more common among females, both current and passive smokers, those working in a dusty job, those with a history of tuberculosis, those who were obese, those with a low level of education and those with hypertension or airflow limitation. The most influential risk factors were current smoking and working in a dusty job. Interpretation: Our findings suggested that the prevalence of chronic cough varies widely across sites in different world regions. Cigarette smoking and exposure to dust in the workplace are its major risk factors. Funding: Wellcome Trust.
KW - Chronic cough
KW - Epidemiology
KW - Excess risk
KW - Global health
UR - http://www.scopus.com/inward/record.url?scp=85185282816&partnerID=8YFLogxK
U2 - 10.1016/j.eclinm.2024.102423
DO - 10.1016/j.eclinm.2024.102423
M3 - Article
C2 - 38268532
AN - SCOPUS:85185282816
SN - 2589-5370
VL - 68
SP - 1
EP - 12
JO - eClinicalMedicine
JF - eClinicalMedicine
M1 - 102423
ER -