Prevalence of retinitis pigmentosa in South Indian population aged above 40 years

Parveen Sen*, Arun Bhargava, Ronnie George, S. Ve Ramesh, Arvind Hemamalini, Raju Prema, Govindasamy Kumaramanickavel, Lingam Vijaya

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


Purpose: The study was undertaken to evaluate the prevalence of retinitis pigmentosa (RP) in rural and urban South India. Methods: Seven thousand seven hundred and seventy four subjects aged 40 years or more from rural and urban Tamil Nadu, underwent comprehensive ophthalmic examination out of 9576 enumerated (81.17%). After a thorough ophthalmic examination, fundus photographs were taken for documentation. Statistical analysis was done using SPSS for Windows (ver 14). Results: 7461 (95.9%) subjects had fundus details seen in both eyes. Thirteen subjects (0.17%; 4 males, 9 females) were diagnosed as retinitis pigmentosa. Retinitis pigmentosa in the urban population was seen in approximately 1 in 930 persons, while 1 in 372 of rural subjects had the disorder. This figure is greater than other reports from the western populations and that of the conservative estimate of 1 in 4000. The age and gender adjusted prevalence rate of retinitis pigmentosa to national census 2001 was 0.155%. Eight subjects (61.53%) had visual acuity less than 3/60. Conclusion: Prevalence of RP in South India appears to be alarmingly higher in comparison to those seen in other parts of the world.

Original languageEnglish
Pages (from-to)279-281
Number of pages3
JournalOphthalmic Epidemiology
Issue number4
Publication statusPublished - Jul 2008
Externally publishedYes


  • Consanguinity
  • Retinitis pigmentosa
  • Rural
  • South India
  • Urban


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