Abstract
The aim of this study was to predict the complete amino acid sequence of rabbit serum amyloid protein A (SAA) and identify heterogenities and amyloidogenic isotypes. After stimulation with turpentine a SAA specific mRNA signal was detected in the rabbit liver, and a cDNA library was made. Selected clones were sequenced. The deduced amino acid sequences of two rabbit SAA proteins differ in five amino acid residues, four of which are located in the NH2-terminal part. Only one of these two isotypes, SAA2, seems to be involved in amyloid formation.
Original language | English |
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Title of host publication | Amyloid and amyloidosis 1990 |
Subtitle of host publication | VIth international symposium on amyloidosis August 5–8, 1990, Oslo, Norway |
Editors | Jacob B. Natvig, Øystein Førre, Gunnar Husby, Anne Husebekk, Bjørn Skogen, Knut Sletten, Per Westermark |
Place of Publication | Dordrecht |
Publisher | Springer, Springer Nature |
Pages | 40-43 |
Number of pages | 4 |
ISBN (Electronic) | 9789401132848 |
ISBN (Print) | 9789401054508 |
DOIs | |
Publication status | Published - 1991 |
Externally published | Yes |
Event | VIth International Symposium on Amyloidosis - Oslo, Norway Duration: 5 Aug 1990 → 8 Aug 1990 |
Conference
Conference | VIth International Symposium on Amyloidosis |
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Country/Territory | Norway |
City | Oslo |
Period | 5/08/90 → 8/08/90 |