TY - JOUR
T1 - Prognostic indicators of cardiovascular risk in renal disease
AU - Hildreth, Cara M.
N1 - Copyright the Author/s. This Document is protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission.
PY - 2012
Y1 - 2012
N2 - Although the annual mortality rate for end-stage renal disease (ESRD) is decreasing, likely due to an increase in kidney transplantation rate, the survival probability for ESRD patients from day one of dialysis has not changed, and is still poor with a 5-year survival rate of approximately 34%. This is contributed to by a high prevalence of cardiovascular disease, which is the leading cause of death in ESRD patients. In order to improve survival outcomes, patients at high risk of cardiovascular related mortality need to be identified. Heart rate variability (HRV), baroreceptor sensitivity, and baroreceptor reflex effectiveness index can be used to assess heart rate control and may predict cardiovascular mortality.This paper will discuss how HRV, baroreceptor sensitivity, and baroreceptor reflex effectiveness index are altered in renal disease and the utility of these indices as markers of cardiac risk in this patient population.
AB - Although the annual mortality rate for end-stage renal disease (ESRD) is decreasing, likely due to an increase in kidney transplantation rate, the survival probability for ESRD patients from day one of dialysis has not changed, and is still poor with a 5-year survival rate of approximately 34%. This is contributed to by a high prevalence of cardiovascular disease, which is the leading cause of death in ESRD patients. In order to improve survival outcomes, patients at high risk of cardiovascular related mortality need to be identified. Heart rate variability (HRV), baroreceptor sensitivity, and baroreceptor reflex effectiveness index can be used to assess heart rate control and may predict cardiovascular mortality.This paper will discuss how HRV, baroreceptor sensitivity, and baroreceptor reflex effectiveness index are altered in renal disease and the utility of these indices as markers of cardiac risk in this patient population.
UR - http://www.scopus.com/inward/record.url?scp=84866300387&partnerID=8YFLogxK
U2 - 10.3389/fphys.2011.00121
DO - 10.3389/fphys.2011.00121
M3 - Article
C2 - 22294981
AN - SCOPUS:84866300387
SN - 1664-042X
VL - 2
SP - 1
EP - 6
JO - Frontiers in Physiology
JF - Frontiers in Physiology
M1 - Article 121
ER -