Prognostic indicators of cardiovascular risk in renal disease

Cara M. Hildreth*

*Corresponding author for this work

    Research output: Contribution to journalArticle

    19 Citations (Scopus)
    3 Downloads (Pure)

    Abstract

    Although the annual mortality rate for end-stage renal disease (ESRD) is decreasing, likely due to an increase in kidney transplantation rate, the survival probability for ESRD patients from day one of dialysis has not changed, and is still poor with a 5-year survival rate of approximately 34%. This is contributed to by a high prevalence of cardiovascular disease, which is the leading cause of death in ESRD patients. In order to improve survival outcomes, patients at high risk of cardiovascular related mortality need to be identified. Heart rate variability (HRV), baroreceptor sensitivity, and baroreceptor reflex effectiveness index can be used to assess heart rate control and may predict cardiovascular mortality.This paper will discuss how HRV, baroreceptor sensitivity, and baroreceptor reflex effectiveness index are altered in renal disease and the utility of these indices as markers of cardiac risk in this patient population.

    Original languageEnglish
    Article numberArticle 121
    Pages (from-to)1-6
    Number of pages6
    JournalFrontiers in Physiology
    Volume2
    DOIs
    Publication statusPublished - 2012

    Bibliographical note

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