Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease

Gilles Lemesle; Laurent Bonello; Axel de Labriolle; Daniel H. Steinberg; Probal Roy; Tina L. Pinto Slottow; Rebecca Torguson; Kimberly Kaneshige; Zhenyi Xue; William O. Suddath; Lowell F. Satler; Kenneth M. Kent; Joseph Lindsay; Augusto D. Pichard; Ron Waksman

doi:10.1002/ccd.21883

Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease

Gilles Lemesle, Laurent Bonello, Axel de Labriolle, Daniel H. Steinberg, Probal Roy, Tina L. Pinto Slottow, Rebecca Torguson, Kimberly Kaneshige, Zhenyi Xue, William O. Suddath, Lowell F. Satler, Kenneth M. Kent, Joseph Lindsay, Augusto D. Pichard, Ron Waksman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Abstract

Background: The Syntax score prognostic value has recently been highlighted in patients undergoing percutaneous coronary intervention (PCI) for multivessel coronary artery disease (CAD), however its prognostic value in patients undergoing coronary artery bypass grafting (CABG) for multivessel CAD is still unknown. The aim of this study was to evaluate the prognostic value of the Syntax score in patients undergoing CABG for 3-vessel CAD. Methods: A cohort of 320 consecutive patients with multivessel (3-vessel) CAD who were subjected for CABG were included in this study and divided into tertiles according to the Syntax score (<24.5, 24.5-34, and >34). During the 1-year follow-up, cardiovascular events including death, myocardial infarction (MI), and stroke were systematically indexed. The primary end point was the composite criteria death/MI/stroke. Results: The Syntax score ranged from 11-74 with a mean of 31.2 ± 12.6 and a median of 28.5 [22-38]. Baseline clinical characteristics were similar among the tertiles. No statistical difference was found for the composite criteria death/MI/stroke: 9.4% versus 7.5% versus 10.4% in the groups with a Syntax score <24.5, 24.5-34, and >34, respectively (P 5 0.754). Conclusion: Unlike for PCI, the Syntax score has a poor prognostic value for severe cardiovascular events in patients undergoing CABG for 3-vessel CAD. Other risk scores should be used to predict the outcome of this population.

Original language	English
Pages (from-to)	612-617
Number of pages	6
Journal	Catheterization and Cardiovascular Interventions
Volume	73
Issue number	5
DOIs	https://doi.org/10.1002/ccd.21883
Publication status	Published - 1 Apr 2009

Keywords

Cardiac catheterization/intervention
Coronary artery bypass grafts
Outcomes
Stents

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Lemesle, G., Bonello, L., de Labriolle, A., Steinberg, D. H., Roy, P., Pinto Slottow, T. L., Torguson, R., Kaneshige, K., Xue, Z., Suddath, W. O., Satler, L. F., Kent, K. M., Lindsay, J., Pichard, A. D., & Waksman, R. (2009). Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease. Catheterization and Cardiovascular Interventions, 73(5), 612-617. https://doi.org/10.1002/ccd.21883

@article{14e696dd56834b3ea4c2572787a92a57,

title = "Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease",

abstract = "Background: The Syntax score prognostic value has recently been highlighted in patients undergoing percutaneous coronary intervention (PCI) for multivessel coronary artery disease (CAD), however its prognostic value in patients undergoing coronary artery bypass grafting (CABG) for multivessel CAD is still unknown. The aim of this study was to evaluate the prognostic value of the Syntax score in patients undergoing CABG for 3-vessel CAD. Methods: A cohort of 320 consecutive patients with multivessel (3-vessel) CAD who were subjected for CABG were included in this study and divided into tertiles according to the Syntax score (<24.5, 24.5-34, and >34). During the 1-year follow-up, cardiovascular events including death, myocardial infarction (MI), and stroke were systematically indexed. The primary end point was the composite criteria death/MI/stroke. Results: The Syntax score ranged from 11-74 with a mean of 31.2 ± 12.6 and a median of 28.5 [22-38]. Baseline clinical characteristics were similar among the tertiles. No statistical difference was found for the composite criteria death/MI/stroke: 9.4% versus 7.5% versus 10.4% in the groups with a Syntax score <24.5, 24.5-34, and >34, respectively (P 5 0.754). Conclusion: Unlike for PCI, the Syntax score has a poor prognostic value for severe cardiovascular events in patients undergoing CABG for 3-vessel CAD. Other risk scores should be used to predict the outcome of this population.",

keywords = "Cardiac catheterization/intervention, Coronary artery bypass grafts, Outcomes, Stents",

author = "Gilles Lemesle and Laurent Bonello and {de Labriolle}, Axel and Steinberg, {Daniel H.} and Probal Roy and {Pinto Slottow}, {Tina L.} and Rebecca Torguson and Kimberly Kaneshige and Zhenyi Xue and Suddath, {William O.} and Satler, {Lowell F.} and Kent, {Kenneth M.} and Joseph Lindsay and Pichard, {Augusto D.} and Ron Waksman",

year = "2009",

month = apr,

day = "1",

doi = "10.1002/ccd.21883",

language = "English",

volume = "73",

pages = "612--617",

journal = "Catheterization and Cardiovascular Interventions",

issn = "1522-1946",

publisher = "Wiley-Liss, Wiley",

number = "5",

}

Lemesle, G, Bonello, L, de Labriolle, A, Steinberg, DH, Roy, P, Pinto Slottow, TL, Torguson, R, Kaneshige, K, Xue, Z, Suddath, WO, Satler, LF, Kent, KM, Lindsay, J, Pichard, AD & Waksman, R 2009, 'Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease', Catheterization and Cardiovascular Interventions, vol. 73, no. 5, pp. 612-617. https://doi.org/10.1002/ccd.21883

TY - JOUR

T1 - Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease

AU - Lemesle, Gilles

AU - Bonello, Laurent

AU - de Labriolle, Axel

AU - Steinberg, Daniel H.

AU - Roy, Probal

AU - Pinto Slottow, Tina L.

AU - Torguson, Rebecca

AU - Kaneshige, Kimberly

AU - Xue, Zhenyi

AU - Suddath, William O.

AU - Satler, Lowell F.

AU - Kent, Kenneth M.

AU - Lindsay, Joseph

AU - Pichard, Augusto D.

AU - Waksman, Ron

PY - 2009/4/1

Y1 - 2009/4/1

N2 - Background: The Syntax score prognostic value has recently been highlighted in patients undergoing percutaneous coronary intervention (PCI) for multivessel coronary artery disease (CAD), however its prognostic value in patients undergoing coronary artery bypass grafting (CABG) for multivessel CAD is still unknown. The aim of this study was to evaluate the prognostic value of the Syntax score in patients undergoing CABG for 3-vessel CAD. Methods: A cohort of 320 consecutive patients with multivessel (3-vessel) CAD who were subjected for CABG were included in this study and divided into tertiles according to the Syntax score (<24.5, 24.5-34, and >34). During the 1-year follow-up, cardiovascular events including death, myocardial infarction (MI), and stroke were systematically indexed. The primary end point was the composite criteria death/MI/stroke. Results: The Syntax score ranged from 11-74 with a mean of 31.2 ± 12.6 and a median of 28.5 [22-38]. Baseline clinical characteristics were similar among the tertiles. No statistical difference was found for the composite criteria death/MI/stroke: 9.4% versus 7.5% versus 10.4% in the groups with a Syntax score <24.5, 24.5-34, and >34, respectively (P 5 0.754). Conclusion: Unlike for PCI, the Syntax score has a poor prognostic value for severe cardiovascular events in patients undergoing CABG for 3-vessel CAD. Other risk scores should be used to predict the outcome of this population.

AB - Background: The Syntax score prognostic value has recently been highlighted in patients undergoing percutaneous coronary intervention (PCI) for multivessel coronary artery disease (CAD), however its prognostic value in patients undergoing coronary artery bypass grafting (CABG) for multivessel CAD is still unknown. The aim of this study was to evaluate the prognostic value of the Syntax score in patients undergoing CABG for 3-vessel CAD. Methods: A cohort of 320 consecutive patients with multivessel (3-vessel) CAD who were subjected for CABG were included in this study and divided into tertiles according to the Syntax score (<24.5, 24.5-34, and >34). During the 1-year follow-up, cardiovascular events including death, myocardial infarction (MI), and stroke were systematically indexed. The primary end point was the composite criteria death/MI/stroke. Results: The Syntax score ranged from 11-74 with a mean of 31.2 ± 12.6 and a median of 28.5 [22-38]. Baseline clinical characteristics were similar among the tertiles. No statistical difference was found for the composite criteria death/MI/stroke: 9.4% versus 7.5% versus 10.4% in the groups with a Syntax score <24.5, 24.5-34, and >34, respectively (P 5 0.754). Conclusion: Unlike for PCI, the Syntax score has a poor prognostic value for severe cardiovascular events in patients undergoing CABG for 3-vessel CAD. Other risk scores should be used to predict the outcome of this population.

KW - Cardiac catheterization/intervention

KW - Coronary artery bypass grafts

KW - Outcomes

KW - Stents

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U2 - 10.1002/ccd.21883

DO - 10.1002/ccd.21883

M3 - Article

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AN - SCOPUS:65549139739

SN - 1522-1946

VL - 73

SP - 612

EP - 617

JO - Catheterization and Cardiovascular Interventions

JF - Catheterization and Cardiovascular Interventions

IS - 5

ER -

Prognostic value of the syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease

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