Progress in lipid and inorganic nanocarriers for enhanced skin drug delivery

Lamyaa Albakr, Hongyuan Du, Xiyuan Zhang, Himanshu Kathuria, Ahmed Fahmi Anwar-Fadzil, Nial J. Wheate, Lifeng Kang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Abstract

New advancements in nanocarrier technologies are revolutionizing the delivery of drugs through the skin, allowing for precise treatment with better absorption, stability, and bioavailability. This review investigates lipid and inorganic nanocarriers like liposomes, ethosomes, and inorganic nanoparticles and assesses their potential for delivering drugs through the skin. It emphasizes the mechanisms that enable controlled release and deeper skin penetration, which are crucial for ensuring effectiveness in clinical applications. The review synthesizes existing research, acknowledging that only few nanocarriers are successfully deployed in clinical settings. By offering a comprehensive overview, it sheds light on the progress and future obstacles to using nanocarriers for drug delivery through the skin.

Original languageEnglish
Article number2400003
Pages (from-to)1-24
Number of pages24
JournalAdvanced NanoBiomed Research
Volume4
Issue number6
DOIs
Publication statusPublished - Jun 2024
Externally publishedYes

Bibliographical note

Copyright the Author(s) 2024. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

  • drug delivery
  • formulations
  • nanocarriers
  • nanoparticles
  • skin
  • topical
  • transdermal

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