Progress in measuring epithelial turnover in the villus of the small intestine

Rufus M. Clarke*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)

Abstract

The epithelium lining the villus of the small intestine is considered as a compartment in the replacement kinetics o f the intestinal epithelium. The three interrelated properties o f the compartment - size, flux and transit time are examined, and numerical estimates of their size in rat and mouse are given. Attention is paid to sources o f error which may affect the precision of such estimates.

Original languageEnglish
Pages (from-to)161-175
Number of pages15
JournalDigestion
Volume8
Issue number2
DOIs
Publication statusPublished - 1973

Keywords

  • Cell division
  • Cell nucleus
  • Circadian rhythm
  • Colchicine
  • Dna
  • Histological techniques
  • Intestinal mucosa
  • Villi intestinal

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