Progress in measuring epithelial turnover in the villus of the small intestine

Rufus M. Clarke

doi:10.1159/000197311

Progress in measuring epithelial turnover in the villus of the small intestine

Rufus M. Clarke^*

^*Corresponding author for this work

Faculty of Medicine, Health and Human Sciences

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

The epithelium lining the villus of the small intestine is considered as a compartment in the replacement kinetics o f the intestinal epithelium. The three interrelated properties o f the compartment - size, flux and transit time are examined, and numerical estimates of their size in rat and mouse are given. Attention is paid to sources o f error which may affect the precision of such estimates.

Original language	English
Pages (from-to)	161-175
Number of pages	15
Journal	Digestion
Volume	8
Issue number	2
DOIs	https://doi.org/10.1159/000197311
Publication status	Published - 1973

Keywords

Cell division
Cell nucleus
Circadian rhythm
Colchicine
Dna
Histological techniques
Intestinal mucosa
Villi intestinal

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10.1159/000197311

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title = "Progress in measuring epithelial turnover in the villus of the small intestine",

abstract = "The epithelium lining the villus of the small intestine is considered as a compartment in the replacement kinetics o f the intestinal epithelium. The three interrelated properties o f the compartment - size, flux and transit time are examined, and numerical estimates of their size in rat and mouse are given. Attention is paid to sources o f error which may affect the precision of such estimates.",

keywords = "Cell division, Cell nucleus, Circadian rhythm, Colchicine, Dna, Histological techniques, Intestinal mucosa, Villi intestinal",

author = "Clarke, \{Rufus M.\}",

year = "1973",

doi = "10.1159/000197311",

language = "English",

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journal = "Digestion",

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T1 - Progress in measuring epithelial turnover in the villus of the small intestine

AU - Clarke, Rufus M.

PY - 1973

Y1 - 1973

N2 - The epithelium lining the villus of the small intestine is considered as a compartment in the replacement kinetics o f the intestinal epithelium. The three interrelated properties o f the compartment - size, flux and transit time are examined, and numerical estimates of their size in rat and mouse are given. Attention is paid to sources o f error which may affect the precision of such estimates.

AB - The epithelium lining the villus of the small intestine is considered as a compartment in the replacement kinetics o f the intestinal epithelium. The three interrelated properties o f the compartment - size, flux and transit time are examined, and numerical estimates of their size in rat and mouse are given. Attention is paid to sources o f error which may affect the precision of such estimates.

KW - Cell division

KW - Cell nucleus

KW - Circadian rhythm

KW - Colchicine

KW - Dna

KW - Histological techniques

KW - Intestinal mucosa

KW - Villi intestinal

UR - https://www.scopus.com/pages/publications/0015847987

U2 - 10.1159/000197311

DO - 10.1159/000197311

M3 - Article

C2 - 4581925

AN - SCOPUS:0015847987

SN - 0012-2823

VL - 8

SP - 161

EP - 175

JO - Digestion

JF - Digestion

IS - 2

ER -

Progress in measuring epithelial turnover in the villus of the small intestine

Abstract

Keywords

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