TY - JOUR
T1 - Progressive muscular relaxation and motility of the small intestine
T2 - Studies in normal subjects and patients with irritable bowel syndrome
AU - KELLOW, J. E.
AU - LANGELUDDECKE, P. M.
AU - ECKERSLEY, G. M.
AU - JONES, M. P.
AU - TENNANT, C. C.
PY - 1992
Y1 - 1992
N2 - Recordings of fasting duodenojejunal motor activity were obtained during a controlled 20-min period of psychological relaxation in 10 patients with irritable bowel syndrome (IBS) and 10 healthy subjects. The IBS group showed a significant decline in their level of arousal (on both cardiovascular and subjective measures) in response to relaxation; such alterations were minimal in the control group. Both groups, however, demonstrated significant inhibition of phase 2 activity (motility index, contractile frequency and amplitude) of the migrating motor complex in response to relaxation, and the magnitude of the response did not differ between the two groups. Clustered contractile activity present in 4 IBS patients was also suppressed during the relaxation period. There were no correlations between changes in the level of arousal and the degree of motor suppression in either IBS patients or controls. These findings demonstrate that psychological relaxation therapy can profoundly influence patterns of small bowel motility, and shed light on the mechanisms by which psychological intervention therapy appears to be effective in IBS.
AB - Recordings of fasting duodenojejunal motor activity were obtained during a controlled 20-min period of psychological relaxation in 10 patients with irritable bowel syndrome (IBS) and 10 healthy subjects. The IBS group showed a significant decline in their level of arousal (on both cardiovascular and subjective measures) in response to relaxation; such alterations were minimal in the control group. Both groups, however, demonstrated significant inhibition of phase 2 activity (motility index, contractile frequency and amplitude) of the migrating motor complex in response to relaxation, and the magnitude of the response did not differ between the two groups. Clustered contractile activity present in 4 IBS patients was also suppressed during the relaxation period. There were no correlations between changes in the level of arousal and the degree of motor suppression in either IBS patients or controls. These findings demonstrate that psychological relaxation therapy can profoundly influence patterns of small bowel motility, and shed light on the mechanisms by which psychological intervention therapy appears to be effective in IBS.
UR - http://www.scopus.com/inward/record.url?scp=0026588877&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2982.1992.tb00078.x
DO - 10.1111/j.1365-2982.1992.tb00078.x
M3 - Article
AN - SCOPUS:0026588877
SN - 1043-4518
VL - 4
SP - 47
EP - 52
JO - Journal of Gastrointestinal Motility
JF - Journal of Gastrointestinal Motility
IS - 1
ER -