TY - JOUR
T1 - Prospective Registry on Mesothelioma Peritonei Treatment (PROMPT)
T2 - Study design and rationale
AU - Cao, Christopher
AU - Yan, Tristan D.
AU - Morris, David L.
AU - Van Der Speeten, Kurt
AU - Laurberg, Søren
AU - Glehen, Olivier
AU - Link, Karl
AU - Piso, Pompiliu
AU - Tentes, Antonios Apostolos K
AU - Deraco, Marcello
AU - Larsen, Stein G.
AU - Kecmanovic, Dragutin
AU - Bayón, Luis G.
AU - Melero, Juan T.
AU - González-Moreno, Santiago
AU - Mahteme, Haile
AU - Gertsch, Philippe
AU - Moran, Brendan
AU - Esquivel, Jesus
AU - Alexander, Richard
AU - Levine, Edward A.
AU - Sugarbaker, Paul H.
PY - 2012/1
Y1 - 2012/1
N2 - Diffuse malignant peritoneal mesothelioma (DMPM) is an aggressive and rare form of cancer arising from the mesothelial lining of the peritoneum. Due to the latency period between asbestos exposure and disease progression, the peak in incidence of DMPM is likely to occur in the coming decade for many industrialized nations, with a multitude of industrial, medico-legal and health-related implications1,2. Traditional therapeutic modalities such as systemic chemotherapy and radiotherapy have not been proven to be effective in the treatment of DMPM, and patients diagnosed with the disease have a life expectancy of less than 12 months3-5. Combined treatment involving cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been utilized in several specialized centers around the world and has been found to be a feasible procedure with encouraging survival outcomes6-8.
AB - Diffuse malignant peritoneal mesothelioma (DMPM) is an aggressive and rare form of cancer arising from the mesothelial lining of the peritoneum. Due to the latency period between asbestos exposure and disease progression, the peak in incidence of DMPM is likely to occur in the coming decade for many industrialized nations, with a multitude of industrial, medico-legal and health-related implications1,2. Traditional therapeutic modalities such as systemic chemotherapy and radiotherapy have not been proven to be effective in the treatment of DMPM, and patients diagnosed with the disease have a life expectancy of less than 12 months3-5. Combined treatment involving cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been utilized in several specialized centers around the world and has been found to be a feasible procedure with encouraging survival outcomes6-8.
UR - http://www.scopus.com/inward/record.url?scp=84863185846&partnerID=8YFLogxK
U2 - 10.1700/1053.11517
DO - 10.1700/1053.11517
M3 - Short survey
C2 - 22495719
AN - SCOPUS:84863185846
SN - 0300-8916
VL - 98
SP - 166
EP - 171
JO - Tumori
JF - Tumori
IS - 1
ER -