Prospective Registry on Mesothelioma Peritonei Treatment (PROMPT)

Study design and rationale

Christopher Cao, Tristan D. Yan*, David L. Morris, Kurt Van Der Speeten, Søren Laurberg, Olivier Glehen, Karl Link, Pompiliu Piso, Antonios Apostolos K Tentes, Marcello Deraco, Stein G. Larsen, Dragutin Kecmanovic, Luis G. Bayón, Juan T. Melero, Santiago González-Moreno, Haile Mahteme, Philippe Gertsch, Brendan Moran, Jesus Esquivel, Richard Alexander & 2 others Edward A. Levine, Paul H. Sugarbaker

*Corresponding author for this work

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Abstract

Diffuse malignant peritoneal mesothelioma (DMPM) is an aggressive and rare form of cancer arising from the mesothelial lining of the peritoneum. Due to the latency period between asbestos exposure and disease progression, the peak in incidence of DMPM is likely to occur in the coming decade for many industrialized nations, with a multitude of industrial, medico-legal and health-related implications1,2. Traditional therapeutic modalities such as systemic chemotherapy and radiotherapy have not been proven to be effective in the treatment of DMPM, and patients diagnosed with the disease have a life expectancy of less than 12 months3-5. Combined treatment involving cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been utilized in several specialized centers around the world and has been found to be a feasible procedure with encouraging survival outcomes6-8.

Original languageEnglish
Pages (from-to)166-171
Number of pages6
JournalTumori
Volume98
Issue number1
DOIs
Publication statusPublished - Jan 2012
Externally publishedYes

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