Protection and controlled release of vitamin C by different micro/nanocarriers

T. Comunian, A. Babazadeh, A. Rehman, R. Shaddel, S. Akbari-Alavijeh, S. Boostani, S. M. Jafari

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)


Ascorbic acid, known as vitamin C, is an important antioxidant and food ingredient, and highly sensitive to environmental conditions, which makes its incorporation into food, cosmetic and pharmaceutical products more difficult. The evaluation of its nano/microencapsulation enables the improvement of its stability and controlled release. There are various investigations regarding ascorbic acid encapsulation; however, a deep study related to the scale-up of encapsulation process, its application into food products and digestibility study are still needed. This review highlights the main physicochemical and health properties of vitamin C, recent advances of its encapsulation into micro/nanocarriers, and application in food products. Also, the controlled release and bioavailability of encapsulated forms within different carriers is underlined. The results of published studies clearly show that vitamin C can be successfully protected within micro/nanoencapsulation systems and it can be applied as an efficient ingredient in the formulation of various food products such as bakery goods.
Original languageEnglish
Pages (from-to)3301-3322
Number of pages22
JournalCritical Reviews in Food Science and Nutrition
Issue number12
Early online date22 Dec 2020
Publication statusPublished - 22 Apr 2022


  • ascorbic acid
  • bioavailability
  • microencapsulation
  • Nanoencapsulation
  • release


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