Protocol for economic evaluation alongside the IMPLEMENT cluster randomised controlled trial

Duncan Mortimer*, Simon D. French, Joanne E. McKenzie, Denise A. O'Connor, Sally E. Green

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
5 Downloads (Pure)


Background. The recent development and publication of evidence-based clinical practice guidelines (CPGs) for acute low back pain (LBP) has resulted in evidence-based recommendations that, if implemented, have the potential to improve the quality and safety of care for acute LBP. While a strategy has been specified for dissemination of the CPG for acute LBP in Australia, there is no accompanying plan for active implementation. Evidence regarding the cost-effectiveness of active implementation of CPGs for acute LBP is sparse. The IMPLEMENT study will consider the incremental benefits and costs of progressing beyond development and dissemination to implementation. Methods/design. Cost-effectiveness and cost-utility analyses alongside the IMPLEMENT cluster randomised controlled trial (CRCT) from a societal perspective to quantify the additional costs (savings) and health gains associated with a targeted implementation strategy as compared with access to the CPG via dissemination only. Discussion. The protocol provided here registers our intent to conduct an economic evaluation alongside the IMPLEMENT study, facilitates peer-review of proposed methods and provides a transparent statement of planned analyses.

Original languageEnglish
Article number12
JournalImplementation Science
Publication statusPublished - 2008
Externally publishedYes

Bibliographical note

Copyright the Author(s) 2008. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


  • implementation strategy
  • cluster randomise control trial
  • friction cost approach
  • Quebec back pain disability scale
  • quality adjusted life year gain


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