Wildlife researchers and conservation biologists are encountering growing research difficulties due to strong and effective advocacy of animal welfare concerns. However, collecting information on the basic biology of animals, which is often essential to effective conservation and management, frequently involves invasive research. The latter is unacceptable to some animal welfare advocates, even if it ultimately leads to better conservation outcomes. For effective biodiversity conservation it is imperative that conservation and wildlife researchers lucidly present the case for their research on individual animals. This requires conservation biologists and the research community in general, to present these arguments in the public domain as well as in peer-reviewed literature. Moreover, it is important to measure how these activities affect animals. Only then can we show that high quality research activities often have little or no effects on animal vital rates and performance.