Pulse pressure amplification and arterial stiffness in middle age

Alberto P. Avolio; Mark Butlin; Athanase D. Protogerou

doi:10.1007/978-1-4471-5198-2_23

Pulse pressure amplification and arterial stiffness in middle age

Alberto P. Avolio^*, Mark Butlin, Athanase D. Protogerou

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

The aging changes in arterial blood pressure that are observed from conventional blood pressure measurement using the brachial cuff sphygmomanometer are not similar to the changes that occur in central aortic pressure, specifically for systolic and pulse pressure. This is due to the phenomenon of pulse pressure amplification that is largely related to aging changes in arterial stiffness. The most pronounced effect of pulse pressure amplification occurs in the middle age range. This chapter assesses the underlying concept and perception of what is considered middle age and describes the associated age-related changes in arterial stiffness and pulse pressure and evaluates how the changes observed in middle age (in this context defined between 40 and 60 years) can inform the understanding of cardiovascular risk and treatment and management of hypertension in the aging population.

Original language	English
Title of host publication	Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases
Editors	Michel E. Safar, Michael F. O'Rourke, Edward D. Frohlich
Place of Publication	London
Publisher	Springer, Springer Nature
Pages	281-295
Number of pages	15
Volume	9781447151982
ISBN (Electronic)	9781447151982
ISBN (Print)	1447151984, 9781447151975
DOIs	https://doi.org/10.1007/978-1-4471-5198-2_23
Publication status	Published - 2014

Keywords

pulse pressure
cardiovascular risk
vascular aging
pulse velocity

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10.1007/978-1-4471-5198-2_23

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title = "Pulse pressure amplification and arterial stiffness in middle age",

abstract = "The aging changes in arterial blood pressure that are observed from conventional blood pressure measurement using the brachial cuff sphygmomanometer are not similar to the changes that occur in central aortic pressure, specifically for systolic and pulse pressure. This is due to the phenomenon of pulse pressure amplification that is largely related to aging changes in arterial stiffness. The most pronounced effect of pulse pressure amplification occurs in the middle age range. This chapter assesses the underlying concept and perception of what is considered middle age and describes the associated age-related changes in arterial stiffness and pulse pressure and evaluates how the changes observed in middle age (in this context defined between 40 and 60 years) can inform the understanding of cardiovascular risk and treatment and management of hypertension in the aging population.",

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Pulse pressure amplification and arterial stiffness in middle age. / Avolio, Alberto P.; Butlin, Mark; Protogerou, Athanase D.
Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases. ed. / Michel E. Safar; Michael F. O'Rourke; Edward D. Frohlich. Vol. 9781447151982 London: Springer, Springer Nature, 2014. p. 281-295.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Pulse pressure amplification and arterial stiffness in middle age

AU - Avolio, Alberto P.

AU - Butlin, Mark

AU - Protogerou, Athanase D.

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N2 - The aging changes in arterial blood pressure that are observed from conventional blood pressure measurement using the brachial cuff sphygmomanometer are not similar to the changes that occur in central aortic pressure, specifically for systolic and pulse pressure. This is due to the phenomenon of pulse pressure amplification that is largely related to aging changes in arterial stiffness. The most pronounced effect of pulse pressure amplification occurs in the middle age range. This chapter assesses the underlying concept and perception of what is considered middle age and describes the associated age-related changes in arterial stiffness and pulse pressure and evaluates how the changes observed in middle age (in this context defined between 40 and 60 years) can inform the understanding of cardiovascular risk and treatment and management of hypertension in the aging population.

AB - The aging changes in arterial blood pressure that are observed from conventional blood pressure measurement using the brachial cuff sphygmomanometer are not similar to the changes that occur in central aortic pressure, specifically for systolic and pulse pressure. This is due to the phenomenon of pulse pressure amplification that is largely related to aging changes in arterial stiffness. The most pronounced effect of pulse pressure amplification occurs in the middle age range. This chapter assesses the underlying concept and perception of what is considered middle age and describes the associated age-related changes in arterial stiffness and pulse pressure and evaluates how the changes observed in middle age (in this context defined between 40 and 60 years) can inform the understanding of cardiovascular risk and treatment and management of hypertension in the aging population.

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KW - cardiovascular risk

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KW - pulse velocity

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SN - 9781447151975

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BT - Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases

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A2 - O'Rourke, Michael F.

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PB - Springer, Springer Nature

CY - London

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Pulse pressure amplification and arterial stiffness in middle age

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Keywords

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