Random walk simulation of R2-dispersion in foam microstructures

S. H. Baete, Y. De Deene

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

The spin-spin relaxation rate R2 (=1/T2) in hydrogel foams measured by use of a multiple spin echo sequence was found to be dependent on the echo time spacing. (Baete and De Deene. Proc. Intl. Soc. Magn. Reson. Med. 15:37, 2007). This property, referred to as R2-dispersion, originates to a large extent from molecular self-diffusion of water within internal field gradients that result from magnetic susceptibility differences between the gel and air phase. Another contribution to the R2 relaxation rate is surface relaxation. Numerical simulations are performed to investigate the relation between the foam microstructure (the mean air bubble radius and standard deviation of the air bubble radius) at one hand and the R2-dispersion at the other hand. The simulated R2-dispersions of gel foam are in agreement with measured R2-dispersions. By correlating the R2-dispersion parameters and simulated microstructure properties a relationship is obtained that enables the mean air bubble size to be derived from measured R2-dispersion curves. The R2-derived mean air bubble size of a hydrogel foam is in agreement with the bubble size measured with X-ray micro-CT. This illustrates the feasibility of using 1H R2-dispersion measurements to determine the size of air bubbles in hydrogel foams and of alveoli in lung tissue.

Original languageEnglish
Title of host publication4th European Conference of the International Federation for Medical and Biological Engineering
Subtitle of host publicationECIFMBE 2008 23–27 November 2008 Antwerp, Belgium
EditorsJos Vander Sloten, Pascal Verdonck, Marc Nyssen, Jens Haueisen
Place of PublicationBerlin
Pages2459-2463
Number of pages5
Volume22
ISBN (Electronic)9783540892083
DOIs
Publication statusPublished - 2008
Externally publishedYes
Event4th European Conference of the International Federation for Medical and Biological Engineering, ECIFMBE 2008 - Antwerp, Belgium
Duration: 23 Nov 200827 Nov 2008

Other

Other4th European Conference of the International Federation for Medical and Biological Engineering, ECIFMBE 2008
CountryBelgium
CityAntwerp
Period23/11/0827/11/08

Fingerprint Dive into the research topics of 'Random walk simulation of R2-dispersion in foam microstructures'. Together they form a unique fingerprint.

Cite this