Rate constants for reaction of hydroxyl radicals with Tris, Tricine and Hepes buffers

Mark Hicks, Janusz M. Gebicki*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    123 Citations (Scopus)

    Abstract

    Rate constants for the reactions of three commonly used organic buffers and hydroxyl radicals were measured using steady-state competition kinetics with thymine. For Hepes (4-(2-hydroxyethyl)-1-piperazine-ethanesulphonic acid), Tricine (N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]glycine and Tris (2-amino-2-hydroxymethylpropane-1,3-diol) the rate constants were 5.1×109, 1.6×109 and 1.1 × 109 1·mol-1·s-1, respectively.

    Original languageEnglish
    Pages (from-to)92-94
    Number of pages3
    JournalFEBS Letters
    Volume199
    Issue number1
    DOIs
    Publication statusPublished - 7 Apr 1986

    Keywords

    • hydroxyl radical
    • hydroxyl radical scavenger
    • organic buffer
    • rate constant

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