TY - JOUR
T1 - Real time 4D radiation gel dosimetry on the Australian MRI-Linac
AU - De Deene, Yves
AU - Wheatley, Morgan
N1 - Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
PY - 2022
Y1 - 2022
N2 - 4D radiation dosimetry using a highly radiation-sensitive polymer gel dosimeter with real-time quantitative MRI readout is presented as a technique to acquire the accumulated radiation dose distribution during image guided radiotherapy (IGRT) on an MRI-Linac. Optimized T2 weighted TSE scans are converted into quantitative ∆R2 maps and subsequently to radiation dose maps. The potential of real-time 4D radiation dosimetry in a theragnostic MRI-Linac is demonstrated in test tubes, for a square beam in a cylindrical gel phantom, for a simple step-and-shoot irradiation in a head phantom and a dynamic arc treatment on a cylindrical gel phantom using a rotating couch. The optimal sequence parameters for maximal dose resolution in the dynamic MRI acquisition will be presented and the trade off between MRI scanning speed and dose resolution will be discussed. A further improvement in temporal resolution using a keyhole imaging approach is the focus of future research.
AB - 4D radiation dosimetry using a highly radiation-sensitive polymer gel dosimeter with real-time quantitative MRI readout is presented as a technique to acquire the accumulated radiation dose distribution during image guided radiotherapy (IGRT) on an MRI-Linac. Optimized T2 weighted TSE scans are converted into quantitative ∆R2 maps and subsequently to radiation dose maps. The potential of real-time 4D radiation dosimetry in a theragnostic MRI-Linac is demonstrated in test tubes, for a square beam in a cylindrical gel phantom, for a simple step-and-shoot irradiation in a head phantom and a dynamic arc treatment on a cylindrical gel phantom using a rotating couch. The optimal sequence parameters for maximal dose resolution in the dynamic MRI acquisition will be presented and the trade off between MRI scanning speed and dose resolution will be discussed. A further improvement in temporal resolution using a keyhole imaging approach is the focus of future research.
UR - http://www.scopus.com/inward/record.url?scp=85124689891&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/2167/1/012029
DO - 10.1088/1742-6596/2167/1/012029
M3 - Conference paper
AN - SCOPUS:85124689891
SN - 1742-6588
VL - 2167
SP - 1
EP - 6
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
M1 - 012029
T2 - 11th International Conference on 3D Radiation Dosimetry, IC3DDose 2021
Y2 - 10 May 2021 through 13 May 2021
ER -